Brain stimulation may boost walking skills in seniors
NCT ID NCT03790657
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This study tested whether mild electrical brain stimulation (tDCS) could help 72 older adults (65+) learn and remember a complex walking task, like stepping over obstacles. Participants practiced walking while receiving either real or fake (sham) stimulation. The goal was to see if the stimulation improved walking speed and to understand brain changes using MRI. The study is complete and focused on gathering knowledge to improve future rehabilitation approaches.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial direct current stimulation (tDCS)
- What this could lead to
- If successful, this could point toward a way to make walking rehabilitation faster and more effective for older adults.
- What could go wrong
- This is an early-phase study with only 72 participants, so results may not apply broadly. The brain stimulation is mild and temporary, and the main focus is on understanding learning mechanisms, not on a proven treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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72 people
The number who actually took part.
- Started
-
Aug 2019
- Finished
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Aug 2024
- Lead sponsor
-
A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
65 years and older
- Sex
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Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age 65 years or older * preferred 10m walking speed \< 1.1 m/s * self-report of "some difficulty with walking tasks, such as becoming tired when walking a quarter mile, or when climbing two flights of stairs, or when performing household chores." * Willingness to be randomized to either study group and to participate in all aspects of study assessment and intervention Exclusion Criteria: * Diagnosed neurological disorder or injury of the central nervous system, or observation of symptoms consistent with such a condition (Alzheimer's, Parkinson's, stroke, etc.) * Contraindications to non-invasive brain stimulation (e.g., metal in head, wound on scalp) * Contraindications to magnetic resonance imaging (e.g., metal in body, claustrophobia, etc). * Use of medications affecting the central nervous system * severe arthritis, such as awaiting joint replacement * severe obesity (body mass index \> 35) * current cardiovascular, lung or renal disease; diabetes; terminal illness * myocardial infarction or major heart surgery in the previous year * cancer treatment in the past year, except for nonmelanoma skin cancers and cancers having an excellent prognosis (e.g., early stage breast or prostate cancer) * current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder * uncontrolled hypertension at rest (systolic \> 180 mmHg and/or diastolic \> 100 mmHg) * bone fracture or joint replacement in the previous six months * current participation in physical therapy for lower extremity function or cardiopulmonary rehabilitation * current enrollment in any clinical trial * difficulty communicating with study personnel, and/or non-English speaking * planning to relocate out of the area during the study period * clinical judgment of investigative team regarding safety or non-compliance
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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North Florida/South Georgia Veterans Health System, Gainesville, FL
Gainesville, Florida, 32608-1135, United States
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