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Brain stimulation may boost walking skills in seniors

NCT ID NCT03790657

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tested whether mild electrical brain stimulation (tDCS) could help 72 older adults (65+) learn and remember a complex walking task, like stepping over obstacles. Participants practiced walking while receiving either real or fake (sham) stimulation. The goal was to see if the stimulation improved walking speed and to understand brain changes using MRI. The study is complete and focused on gathering knowledge to improve future rehabilitation approaches.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If successful, this could point toward a way to make walking rehabilitation faster and more effective for older adults.
What could go wrong
This is an early-phase study with only 72 participants, so results may not apply broadly. The brain stimulation is mild and temporary, and the main focus is on understanding learning mechanisms, not on a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

72 people

The number who actually took part.

Started

Aug 2019

Finished

Aug 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age 65 years or older * preferred 10m walking speed \< 1.1 m/s * self-report of "some difficulty with walking tasks, such as becoming tired when walking a quarter mile, or when climbing two flights of stairs, or when performing household chores." * Willingness to be randomized to either study group and to participate in all aspects of study assessment and intervention Exclusion Criteria: * Diagnosed neurological disorder or injury of the central nervous system, or observation of symptoms consistent with such a condition (Alzheimer's, Parkinson's, stroke, etc.) * Contraindications to non-invasive brain stimulation (e.g., metal in head, wound on scalp) * Contraindications to magnetic resonance imaging (e.g., metal in body, claustrophobia, etc). * Use of medications affecting the central nervous system * severe arthritis, such as awaiting joint replacement * severe obesity (body mass index \> 35) * current cardiovascular, lung or renal disease; diabetes; terminal illness * myocardial infarction or major heart surgery in the previous year * cancer treatment in the past year, except for nonmelanoma skin cancers and cancers having an excellent prognosis (e.g., early stage breast or prostate cancer) * current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder * uncontrolled hypertension at rest (systolic \> 180 mmHg and/or diastolic \> 100 mmHg) * bone fracture or joint replacement in the previous six months * current participation in physical therapy for lower extremity function or cardiopulmonary rehabilitation * current enrollment in any clinical trial * difficulty communicating with study personnel, and/or non-English speaking * planning to relocate out of the area during the study period * clinical judgment of investigative team regarding safety or non-compliance

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • North Florida/South Georgia Veterans Health System, Gainesville, FL

    Gainesville, Florida, 32608-1135, United States

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