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Vitamin d pills tested as muscle saver for seniors with obesity

NCT ID NCT07275177

Symptom relief Sponsor: Universidad Autónoma Benito Juárez de Oaxaca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking a high dose of vitamin D3 daily for 12 weeks could improve muscle strength and mass in older adults with obesity. Researchers enrolled 29 participants aged 60 and older in southern Mexico. They measured handgrip strength, muscle mass, and physical performance before and after the supplement period. The goal is to see if correcting low vitamin D levels can help prevent age-related muscle decline.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vitamin D3 (cholecalciferol)
What this could lead to
If it works, this could point toward a simple, low-cost way to help older adults with obesity maintain muscle strength and physical function.
What could go wrong
This is a small, completed study with only 29 participants, so results may not apply to everyone. Vitamin D supplements may not significantly improve muscle health in all older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

29 people

The number who actually took part.

Started

Jan 2024

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 60 years or older. * Diagnosis of obesity (BMI ≥ 30 kg/m²). * Patients attending the outpatient clinic of IMSS No. 24 in Miahuatlán de Porfirio Díaz, Oaxaca. * Able to perform physical and functional tests (handgrip, SPPB). * Capable of providing informed consent. * Willing to comply with the intervention and attend baseline and 12-week evaluations. Exclusion Criteria: * Known diagnosis of hypercalcemia or disorders of calcium metabolism. * Current use of high-dose vitamin D supplementation or medications affecting vitamin D metabolism. * Severe renal or hepatic disease. * Active cancer treatment. * Neurological or musculoskeletal conditions that impair mobility or functional testing (e.g., recent fractures, severe osteoarthritis, stroke with major disability). * Cognitive impairment preventing the understanding of instructions or informed consent. * Any medical condition that, in the judgment of investigators, would interfere with participation or pose additional risk. * Participation in another clinical trial during the study period.

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Conditions

The condition(s) this trial relates to.

Muscle Weakness Obesity obesity disorder Sarcopenia vitamin D deficiency vitamin D hydroxylation-deficient rickets, type 1B

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Age-related loss of skeletal muscle mass Aging Functional decline Muscle mass Muscle strengh Muscle weakness Obesity Obesity (disorder) Older adults (65 years and older) Sarcopenia Sarcopenia in elderly Sarcopenic obesity Vitamin D 25-hydroxylase deficiency Vitamin D deficiency

Contacts and locations

Locations

  • Instituto Mexicano del Seguro Social - Unidad de Medicina Familiar 24, Miahuatlán de Porfirio Díaz, Oaxaca, México

    Miahuatlán de Porfirio Díaz, Oaxaca, 70805, Mexico

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