SARCOPENIA IN ELDERLY

This study tests an experimental drug called PLH-2301 in people aged 65 and older who have sarcopenia, a condition that causes muscle loss and weakness. Participants will take either a placebo or one of three doses of the drug daily for 12 weeks. The main goal is to see if the dr…

This study looks at whether blood flow restriction training (BFR) can help older adults build muscle safely during hospital rehab after a hip fracture. Participants will do low-intensity exercises with a special cuff on their leg. The goal is to see if this method improves streng…

This study tests whether an 8-week machine-based resistance training program can improve muscle strength and physical function in older adults (60+) who have both chronic heart failure and sarcopenia (age-related muscle loss). About 146 participants will be randomly assigned to e…

This study tests whether a daily 15 mL drink called JUICE HA® can help people aged 65 and older who have sarcopenia (age-related muscle loss). Sixty participants will be randomly assigned to receive either the supplement or a placebo for 12 weeks. Researchers will measure changes…

This study tests whether taking creatine supplements for 12 weeks helps people aged 65 and older regain muscle mass, strength, and mobility after total knee replacement surgery. Participants will take creatine or a placebo daily alongside their usual rehab program. The goal is to…

This study tests whether a 6-week supervised pool exercise program can improve muscle strength, muscle mass, physical performance, and quality of life in adults aged 65 and older with sarcopenia (age-related muscle loss). Participants will exercise in water, which is easier on jo…

This study tests whether a special protein drink, MediDrink Platinum+, can improve muscle strength and daily function in older adults (60+) who are losing muscle and are malnourished. Participants will take the drink alone or with an added protein ingredient for 12 weeks. The goa…

This study looks at whether easy-to-do tests for muscle strength and frailty can help predict complications after major abdominal surgery in people aged 65 and older. About 100 participants will complete brief assessments during a routine pre-surgery visit, and researchers will c…

This study looks at how swallowing is affected in older adults who have lost muscle mass (sarcopenia) and have trouble swallowing (dysphagia). Researchers will use video X-rays and muscle sensors to measure throat muscle activity during swallowing. The goal is to better understan…

This small pilot study looks at whether whole-body electrical muscle stimulation (WB-EMS) combined with exercise can improve how nerves activate muscles in healthy older adults. Twelve participants will undergo testing before and after four weeks of twice-weekly WB-EMS sessions. …

This study looks at how tirzepatide, a weight-loss drug, affects muscle mass and strength in adults aged 50 and older with obesity. Researchers want to know if losing weight with this drug also leads to muscle loss, which could cause weakness or frailty. About 20 participants wil…

This study looks at whether giving older adults with sarcopenia (age-related muscle loss) real-time feedback on how fast they move during leg presses can improve muscle activation and motivation. Sixty participants aged 60-95 will visit the lab once a week for three weeks to do l…

This study follows 327 adults aged 65 and older who have surgery to remove gastrointestinal cancers. Researchers track their physical function, quality of life, and cancer outcomes for up to 5 years. The goal is to identify factors that predict decline, helping doctors better sup…