Sarcopenia in elderly

Researchers are testing whether denosumab, a drug usually used for osteoporosis, can also treat sarcopenia, the loss of muscle mass and strength that comes with age. The trial enrolls 120 adults aged 65 and older who have both sarcopenia and osteoporosis. Participants receive eit…

This study tests a volunteer-led lifestyle program for older adults (60+) with sarcopenia, a condition causing muscle loss and weakness. The program includes workshops on nutrition and exercise, supported by nurses and trained volunteers. Researchers will measure changes in muscl…

This trial tests whether a high-protein egg white pudding is a practical and acceptable way to supplement the diets of older adults living in personal care homes. About 54 residents aged 50 and older who already need nutritional supplements will receive either the egg white puddi…

This clinical trial is testing whether an experimental oral drug called AMC6156 can improve physical function and safety in older adults with sarcopenia, a condition marked by loss of muscle mass and strength. Participants will take either AMC6156 or a placebo daily for 12 weeks,…

This study tests an experimental oral medication, PLH-2301, in 168 adults aged 65 and older who have sarcopenia (age-related muscle loss). Participants take either a placebo or one of three doses daily for 12 weeks. The main goal is to see if the drug improves physical function, …

This study tests whether a daily 15 mL drink called JUICE HA® can improve muscle mass, strength, and quality of life in people aged 65 and older with sarcopenia (age-related muscle loss). Sixty participants will be randomly assigned to receive either the supplement or a placebo f…

This study tests whether a 6-week supervised pool exercise program can improve muscle strength, mass, and quality of life in adults aged 65 and older with sarcopenia (age-related muscle loss). Participants will do 15 sessions of water-based exercises over 6 weeks. Researchers wil…

This study tests whether using blood flow restriction cuffs during low-intensity stationary cycling can safely improve muscle strength and mobility in older adults recovering from a hip fracture. Sixty hospitalized patients over age 65 will be randomly assigned to either real or …

This study tests whether taking creatine supplements for 12 weeks helps adults aged 65 and older regain muscle mass, strength, and physical function after total knee replacement surgery. Participants will take creatine or a placebo daily alongside standard rehabilitation. The goa…

This pilot study tests whether whole-body electrical muscle stimulation (WB-EMS) combined with exercise can improve muscle activation and physical function in healthy older adults aged 65 and older. Participants will use a special suit with electrodes that stimulate major muscle …

This study tests whether a special protein drink called MediDrink Platinum+ can improve muscle strength, physical function, and overall well-being in adults aged 60 and older who have muscle loss (sarcopenia) and are malnourished. Participants will take the drink alone or with an…

This study at Montpellier University Hospital will look at whether low muscle mass and strength before hip replacement surgery affects how well people aged 75 and older regain their independence. About 20 volunteers will have blood tests, scans, and a tiny muscle sample taken dur…

Researchers at the University of Oregon are studying how a protein in skeletal muscle called myosin binding protein C, or MyBP-C, changes with fatigue and aging. The study compares healthy adults aged 18 to 35 with adults aged 65 to 80. Participants perform knee extension exercis…

This study looks at how tirzepatide, a weight-loss drug, affects muscle mass and strength in adults aged 50 and older with obesity. Researchers want to know if losing weight with this drug also causes harmful muscle loss that could lead to frailty. Twenty participants will take t…

This study tests whether showing older adults with sarcopenia (age-related muscle loss) their movement speed during leg presses can improve muscle activation, motivation, and perceived effort. Sixty participants will visit the lab once a week for three weeks to perform leg press …

This study looks at why some older adults with sarcopenia (age-related muscle loss) have trouble swallowing. Researchers will use video X-rays and muscle activity sensors to see how swallowing works in different phases. The goal is to better understand the problem, which could le…

This study follows 327 patients aged 65 and older who have surgery to remove gastrointestinal cancer. Researchers want to find out what factors predict whether patients will have a decline in physical function or quality of life one year later, and how they do over five years. Th…