University Of Maryland, Baltimore

This study is testing a single, focused dose of radiation given before surgery to remove early-stage breast cancer. The radiation is delivered using a special machine called the GammaPod, which targets the tumor precisely and spares healthy tissue. The goal is to find a safe and …

This early-phase study tests whether adding deep heat therapy and a special type of radiation to standard chemoimmunotherapy is safe and doable for people with advanced bile duct cancer that cannot be removed by surgery. About 15 adults will receive the standard drugs gemcitabine…

This study tests two ways to manage severe open fractures of the shin bone. 312 adults who need multiple surgeries will get either an antibiotic bead pouch or a vacuum-sealed dressing. The goal is to see which method leads to fewer complications, fewer repeat surgeries, and bette…

This study tests a special MRI scan that uses a natural substance (pyruvate) to see if it can better diagnose brain tumors called gliomas. About 5 adults with suspected or known gliomas will get this extra scan before their planned surgery. The goal is to see if the new MRI is sa…

This study tests a home-based robot that stretches and moves the ankle, combined with mild electrical stimulation to activate leg muscles, for people who had a stroke at least 6 months ago. The goal is to improve walking, range of motion, and muscle strength. 60 participants will…

This early-phase study tests whether diclofenac, an FDA-approved pain reliever, can help people with alcohol use disorder by changing brain chemistry. Researchers will give 24 adults either a placebo or one of three doses of diclofenac and measure its effects on craving, mood, an…

This study tests whether using virtual reality (VR) alongside standard care can reduce pain for adults with sickle cell disease who are in the emergency department for a painful crisis. About 30 participants will be split into three groups to compare pain scores and comfort. The …

This early-stage study tests whether MRI-guided focused ultrasound can safely treat task-specific focal hand dystonia, a condition causing involuntary cramping during activities like writing or playing an instrument. Ten adults who haven't improved with standard treatments will r…

This study tests whether an attachment-based parenting program (ABC) can improve health outcomes in 260 low-income Latino children starting at 9 months old. Researchers will track common illnesses, sleep, weight, and inflammation over 15 months, comparing the program to a reading…

This study explores whether virtual reality exercise can help older adults (55+) stay physically active and maintain muscle function during a hospital stay. Researchers will enroll 140 participants to test if this approach is acceptable and effective. The goal is to prevent the c…

This pilot study uses Brillouin microscopy, a non-contact imaging method, to measure how stiff the cornea is in people with glaucoma. Researchers will compare corneal stiffness between patients with high-tension glaucoma, normal-tension glaucoma, and healthy volunteers. The goal …