Eye fluid biobank aims to unlock secrets of dry eye after transplant

NCT ID NCT04946721

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collects eye fluid, cells, and blood samples from 150 adult cancer patients who have dry eye disease after a stem cell transplant (graft-versus-host disease). Researchers will analyze these samples to find risk factors, markers, and possible treatment targets. The goal is to better understand why this eye damage happens and how to prevent or treat it in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to new diagnostic tools and targeted treatments for dry eye disease in patients with graft-versus-host disease.
What could go wrong
This is an observational biobank study, not a treatment trial. It will not directly benefit participants and may not identify clear biomarkers or targets.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Geenebaum Cancer Center, University of Maryland Medical Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

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