DRY EYE DISEASE

This study tests a new artificial tear, ABBV-444, against an existing brand (Refresh Optive) in 250 adults with dry eye disease. Participants use the assigned drops for 90 days. The goal is to see if the new formula improves eye comfort and reduces dryness symptoms better than th…

This study is testing two new artificial tear formulas to see if they are safe for people with moderate dry eye disease. About 148 adults who already use artificial tears will take part. Researchers will watch for side effects and check eye health during the study.

This study tests if a new eye drop, BUFY01, works as well as an existing one, SVS20, for people with dry eye disease. About 80 participants will use one of the two drops daily for three months. Researchers will check eye health and symptoms to see if both treatments provide simil…

This study tests whether an eye ointment called Vit-A-Vision can relieve symptoms of dry eye disease, such as burning, irritation, and tired eyes. About 77 adults with dry eye will use the ointment for 30 days. Researchers will measure tear film stability and symptom scores to se…

This study tests a new eye drop that combines two existing medicines (lifitegrast and perfluorohexyloctane) for people with dry eye disease. About 423 adults with dry eyes for at least 6 months will use the drops twice a day for 4 weeks. The goal is to see if the combination work…

This study tests whether a new treatment, BUFY02, works as well as an existing one, TRB02, for people with dry eye disease. About 80 participants will use the assigned eye drops daily for three months. Researchers will check eye health and ask about symptoms to see if both treatm…

This study tests a new eye drop called GRF312 5% in 100 adults with dry eye disease. The goal is to see if it is safe and helps relieve symptoms. Participants will use the drops at home and attend clinic visits for check-ups.

This study looks at why some cancer patients develop severe dry eye after a stem cell transplant (called ocular graft-versus-host disease). Researchers will collect eye samples from 150 adults to find new treatment targets and early warning signs. The goal is to better understand…

This study looks at whether the amount of iron in a person's tears is related to how bad their dry eye disease is. Researchers will compare tear samples from 52 people with dry eyes and healthy eyes. The goal is to find a new way to diagnose and understand dry eye better.