DRY EYE DISEASE

This study is testing an experimental eye drop called GRF312 5% to see if it is safe and can help relieve symptoms in adults with moderate to severe dry eye disease. About 100 participants will be randomly assigned to receive either the active eye drops or a placebo (vehicle) ver…

This study aims to see if a new eye drop called BUFY02 works as well as an existing treatment called TRB02 for people with dry eye disease. About 80 participants will use one of the two treatments daily for three months and attend several clinic visits for check-ups and questionn…

This study is testing whether Vit-A-Vision ointment can safely relieve symptoms of dry eye disease, such as burning, irritation, and tired eyes. About 77 adults with diagnosed dry eye will use the ointment daily for 30 days. Researchers will measure changes in eye comfort, tear f…

This study is testing a new combination eye drop (lifitegrast/perfluorohexyloctane) to see if it helps reduce the signs and symptoms of dry eye disease. About 423 adults with a history of dry eye for at least 6 months will use the drops twice daily for 4 weeks and be compared to …

This study aims to see if a new eye drop called BUFY01 works as well as an existing treatment (SVS20) for dry eye disease. About 80 adults with a history of dry eyes will use one of the drops daily for three months and attend clinic visits. Researchers will compare how well each …

This study is testing the safety and comfort of two new artificial tear formulas for people with moderate dry eye disease. About 148 participants who already use artificial tears will try both formulas over approximately three weeks. Researchers will monitor for any side effects …

This study aims to see if a new artificial tear formula, ABBV-444, works better and is as safe as a widely used brand, Refresh Optive, for people with dry eye disease. About 250 adults with moderate to severe dry eye symptoms will use one of the two eye drops for 90 days. Researc…

This study aims to learn more about dry eye disease by observing how various eye tests and biological markers change over time in people who start one of two standard prescription eye drops. It will enroll 350 people, including those with moderate to severe dry eye and healthy vo…

This study aims to find out if the amount of iron in a person's tears is connected to how severe their dry eye disease is. Researchers will compare tear samples from people with dry eyes to samples from people with healthy eyes. They hope this research could lead to a new way to …

This study aims to understand why some cancer patients develop severe, painful dry eye disease after a bone marrow transplant, a condition called ocular graft-versus-host disease. Researchers will collect small samples from the eye's surface and blood from 150 adult patients over…