DRY EYE DISEASE

This study is testing two versions of Tears Naturale lubricating eye drops—one with preservatives and one without—in 120 people with mild to moderate dry eye disease. Participants will stop using their usual artificial tears and use only the study drops for the duration of the tr…

This early study tests eye drops made from stem cell particles in 20 adults with dry eye disease. Participants use the drops four times daily for four weeks. Researchers track safety and symptom changes like eye staining and tear film stability.

This study tests whether a new eye drop, BUFY01, works as well as an existing one, SVS20, for people with dry eye disease. About 80 participants will use one of the two drops daily for three months. Researchers will check eye health and ask about symptoms to see if the treatments…

This study tests whether a new treatment (BUFY02) works as well as an existing one (TRB02) for dry eye disease. About 80 adults with dry eye for at least 3 months will use the assigned eye drops daily for 3 months. Researchers will check eye health and symptoms to see if both tre…

This study tests whether placing a tiny plug in the upper tear duct can further relieve dry eye symptoms in people who already have a plug in the lower tear duct. Researchers will follow 36 adults with aqueous-deficient dry eye for 6 months, measuring eye comfort and tear film ch…

This study compares two lubricating eye drops—Systane PRO PF and Thealoz Duo—to see which one better relieves dry eye symptoms. About 100 adults with dry eye will use each drop for 4 weeks, one twice a day and the other four times a day. The goal is to find out if they work equal…

This study is testing two new artificial tear formulas to see if they are safe and well-tolerated in people with moderate dry eye disease. Researchers will monitor for side effects and eye health in 148 participants who already use artificial tears. The goal is to find better opt…

This Phase 2 trial tests a new eye drop that combines two active ingredients—lifitegrast and perfluorohexyloctane—for people with dry eye disease. About 423 adults will use the drops twice daily for 4 weeks. Researchers will measure changes in eye surface staining and symptom sco…

This study tests whether Vit-A-Vision, an eye ointment used up to three times daily, can improve dry eye symptoms like burning and irritation. About 77 adults with dry eye disease will use the ointment for 30 days. Researchers will measure tear film stability and symptom scores t…

This study is looking at whether GLP-1 receptor agonists—drugs used for type 2 diabetes and obesity—can also improve dry eye disease. Researchers will measure changes in tear stability and eye surface health in 100 patients who have not taken these drugs before. The goal is to un…

This study looks at whether the amount of iron in tears is linked to how severe dry eye disease is. Researchers will collect tear samples from 52 people with and without dry eye and compare iron levels to standard eye tests and symptom scores. The goal is to find a new way to dia…

This study collects eye fluid, cells, and blood samples from 150 adult cancer patients who have dry eye disease after a stem cell transplant (graft-versus-host disease). Researchers will analyze these samples to find risk factors, markers, and possible treatment targets. The goal…