DRY EYE DISEASE

This study tested a new eye drop containing a protein called nerve growth factor (rhNGF) to see if it could safely improve symptoms of dry eye disease. Over 300 adults with moderate-to-severe dry eye used either one of two strengths of the new drop or a placebo drop three times a…

This study tested three different ways of using a medicated eyelid wipe (IVW-1001) to see which method works best for relieving dry eye disease. Thirty people with dry eyes participated, and researchers compared the safety and effectiveness of the different wiping techniques. The…

This study looked at whether using a special device called the Systane iLux system before cataract surgery could help improve dry eye symptoms caused by clogged oil glands in the eyelids. Researchers compared 25 patients who received the treatment two weeks before their surgery t…

This study tested whether a new eye drop called SI-614 could safely reduce signs and symptoms of dry eye disease better than a placebo (inactive) drop. About 230 adults with a history of dry eye used the assigned drops in both eyes four times a day for 29 days. Researchers measur…

This study tested whether a new eye drop called reproxalap could safely reduce the discomfort of dry eye disease. Over 400 adults with dry eye symptoms used either the active eye drops or a placebo (vehicle) solution for six weeks. The main goal was to see if the drops lowered pa…

This completed Phase 3 trial tested whether reproxalap eye drops could reduce discomfort in people with dry eye disease. The study compared the active drops against placebo drops in 116 participants. Researchers measured eye discomfort using a special dry eye chamber to see if th…

This study tested the safety of a new eye drop called reproxalap for people with dry eye disease. Over 750 participants used the eye drop or a placebo (inactive) drop for up to a year. The main goal was to check for serious side effects related to vision, eye pressure, and the he…

This study tested whether eye drops made from a patient's own blood serum work better than standard artificial tears for severe dry eye. Forty-six patients with severe dry eye tried three different treatments for eight weeks each: two strengths of their own serum drops and standa…

This study tested whether a new eye drop called AR-15512 could quickly increase tear production in people with dry eye disease. Researchers measured tear levels in 81 participants' eyes before and after using the drops during a single clinic visit. The goal was to see if this tre…

This study tested whether adding a new eye drop called cenegermin (Oxervate) to standard cyclosporine treatment could better help people with severe dry eye from Sjogren's syndrome. For 4 weeks, 85 participants used either the new drop or a placebo (vehicle) three times a day, wh…

This study aimed to check the safety of a new eye drop for dry eye disease by comparing it to a standard artificial tear. It involved 55 participants with dry eyes who tried different sequences of the new drop and the standard one. The main goal was to see what percentage of peop…

This study tested whether special medicated eyelid wipes called IVW-1001 can safely reduce dry eye symptoms. 150 adults with dry eye disease used either a low-dose wipe, a high-dose wipe, or a placebo wipe for 28 days. Researchers measured changes in tear production, eye surface …

This study tested whether a new eye drop called SHJ002 is safe and effective for treating dry eye disease. It compared the drops to a placebo in 85 adults with dry eye for at least 6 months. The goal was to see if the treatment could reduce eye damage and improve symptoms like dr…

This study tested a new eye lubricant to see if it is safe and effective for reducing the symptoms of dry eye disease. About 188 adults with mild to moderate dry eye used the drops for 30 days. Researchers measured how much the drops reduced the bother caused by dry eye symptoms.