DRY EYE DISEASE

This study tested an eye drop called cenegermin (Oxervate) in 85 adults with severe dry eye caused by Sjogren's syndrome. Participants also used cyclosporine eye drops. The goal was to see if cenegermin could increase tear production and reduce dry eye symptoms better than a plac…

This study tested a new eye drop called AR-15512 in 80 adults with dry eye disease. The main goal was to see if the drops could increase the number of goblet cells on the eye's surface, which help keep the eye moist. The study is completed, and results are being analyzed to see i…

This study tested whether a new eye drop called AR-15512 is safe for people with dry eye disease. 55 adults received either the new drop or a standard artificial tear (REFRESH Classic). The main goal was to compare eye-related side effects between the two groups. Results help und…

This study tested an experimental eye drop called SHJ002 in 85 adults with dry eye disease. The goal was to see if it safely improves eye surface health and reduces symptoms like dryness. Participants used the eye drops for several weeks, and researchers measured changes in corne…

This study tested an experimental eye drop called INV-102 in 84 adults with moderate dry eye disease. The goal was to check safety and see if the drops can reduce eye dryness. Participants used the drops for two weeks, and researchers measured changes in dryness symptoms.

This study tested whether eye drops made from a patient's own blood (autologous serum) can relieve severe dry eye symptoms better than standard artificial tears. 46 adults with severe dry eye tried both diluted and undiluted serum drops, as well as artificial tears, in a random o…

This study tested if using the Systane iLux system, a device that applies heat and pressure to the eyelids, can improve dry eye symptoms in people about to have cataract surgery. Thirty adults with dry eye due to meibomian gland dysfunction took part. The goal was to see if the t…

This study tested three different ways to use an eyelid wipe (IVW-1001) for people with dry eye disease. Thirty adults took part to see how safe and effective each method was. The main goal was to measure changes in tear production and vision.

This study tested an eye drop called reproxalap (0.25%) against a placebo in 116 adults with dry eye disease. The goal was to see if it reduces eye discomfort over 100 minutes in a dry environment. Participants used the drops and rated their discomfort on a scale from 0 to 100.

This study tested a new lubricating eye drop in 188 adults with mild to moderate dry eye disease. Participants used the eye drops for 30 days and reported their symptoms. The results showed that the eye drops reduced eye discomfort, with patients feeling less bothered by their dr…

This study tested an eye drop called reproxalap in 421 adults with dry eye disease. Participants used the drops or a placebo for up to 6 weeks. The main goal was to see if the drops reduce eye discomfort better than placebo.

This study tested an eye drop called SI-614 in 232 adults with dry eye disease. Participants used the drops or a placebo for 29 days. Researchers measured changes in eye staining and daily discomfort to see if the drops helped relieve symptoms.

This study tested a medicated eyelid wipe called IVW-1001 in 150 adults with dry eye disease. The goal was to see if it safely improves tear production and eases symptoms like discomfort. Participants used the wipe on their eyelids, and doctors measured changes in tear amount and…

This study tested the safety of an eye drop called reproxalap in 757 adults with dry eye disease. Participants used the drops for up to 12 months to check for serious side effects like vision changes or eye pressure increases. The goal was to see if the treatment is safe, not to …

This study tested two strengths of a new eye drop (rhNGF) in 317 adults with moderate-to-severe dry eye disease. Participants used the drops for 4 weeks and were followed for another 4 weeks. The goal was to see if the drops improve dry eye symptoms and tear production better tha…

This study tested whether a new eye drop called AR-15512 can quickly increase tear production in people with dry eye disease. 81 adults received the drops, and their tear volume was measured using a special camera. The goal was to see if the drops could provide fast relief from d…

A randomized, controlled, double-masked, investigator-initiated trial to evaluate tear film quality and stability in subjects with dry eye disease using OC-01 (varenicline solution) nasal spray 0.03 mg as compared to vehicle control nasal spray.