New eye drops aim to soothe dry eyes
NCT ID NCT05486728
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tested an experimental eye drop called SHJ002 in 85 adults with dry eye disease. The drops are designed to block a specific microRNA linked to inflammation. Researchers measured changes in corneal staining and symptom scores over 84 days to see if the drops are safe and effective compared to a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SHJ002 (antisense oligonucleotide eye drops)
What this could lead to
If successful, this could lead to a new eye drop treatment that reduces dry eye symptoms and corneal damage.
What could go wrong
This is an early Phase 2 trial with only 85 people. The drug may not work better than placebo, and long-term safety is unknown.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Australian Eye Specialists
Werribee, Victoria, 3030, Australia
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Kaohsiung Veterans General Hospital
Kaohsiung City, Kaohsiung, 813414, Taiwan
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King Chulalongkorn Memorial Hospital
Bangkok, 10330, Thailand
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Ramathibodi Hospital, Mahidol University
Bangkok, 10400, Thailand