Second plug may boost dry eye comfort

NCT ID NCT07571330

Recruiting now Symptom relief Sponsor: Universidad Autonoma de Nuevo Leon Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether placing a tiny plug in the upper tear duct can further relieve dry eye symptoms in people who already have a plug in the lower tear duct. Researchers will follow 36 adults with aqueous-deficient dry eye for 6 months, measuring eye comfort and tear film changes. The goal is to see if the extra plug helps keep the eye surface more moist.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: punctal plug (a tiny silicone or collagen plug placed in the tear duct opening)
What this could lead to: If it works, this could offer a simple, non-drug way to further improve eye moisture and comfort for people with stubborn dry eye.
What could go wrong: This is a small, early-stage study with only 36 participants. The benefit may be small or not last long, and plugs can sometimes cause irritation or fall out.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AQUEOUS-DEFICIENT DRY EYE DISEASE DED

Contacts and locations

Locations

Ophthalmology Department
RECRUITING

Monterrey, Nuevo León, 64460, Mexico

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