New eye drops for dry eye pass safety check in large trial
NCT ID NCT04735393
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested the safety of reproxalap eye drops in 757 adults with dry eye disease. Participants used the drops for up to one year. The main goal was to check for serious side effects like vision changes or eye pressure increases. Results will show whether the drops are safe enough to move forward.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
reproxalap ophthalmic solution (0.25%)
What this could lead to
If it works, this could offer a new eye drop option to ease dry eye symptoms with a good safety profile.
What could go wrong
This is a safety-focused trial, not designed to prove the drops work. Even if safe, reproxalap may not relieve symptoms better than existing treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Andover Eye Associates
Andover, Massachusetts, 01810, United States