New eye drops for dry eye pass safety check in large trial
NCT ID NCT04735393
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested the safety of reproxalap eye drops in 757 adults with dry eye disease. Participants used the drops for up to one year. The main goal was to check for serious side effects like vision changes or eye pressure increases. Results will show whether the drops are safe enough to move forward.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- reproxalap ophthalmic solution (0.25%)
- What this could lead to
- If it works, this could offer a new eye drop option to ease dry eye symptoms with a good safety profile.
- What could go wrong
- This is a safety-focused trial, not designed to prove the drops work. Even if safe, reproxalap may not relieve symptoms better than existing treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DRY EYE DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Andover Eye Associates
Andover, Massachusetts, 01810, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Dry eye gel may sharpen cataract surgery results
- New eye drops could bring relief to millions with chronic dry eye
- Could stem cell eye drops soothe dry eyes?
- Second plug may boost dry eye comfort
- New AI reads eye scans to diagnose dry eye instantly
- Popular diabetes drugs may ease dry eye, study suggests