Dry eye study seeks better ways to measure disease
NCT ID NCT07025811
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tracks 378 people with moderate to severe dry eye disease and healthy volunteers to see how signs, symptoms, and biomarkers change after treatment with either Vevye or Xiidra eye drops. The goal is to find better ways to measure the disease and its response to therapy. Participants will receive standard anti-inflammatory eye drops and be monitored over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cyclosporine ophthalmic solution (Vevye) and lifitegrast ophthalmic solution (Xiidra)
What this could lead to
If successful, this study could help doctors better understand and measure dry eye disease, leading to more personalized treatments.
What could go wrong
This is an observational study focused on biomarkers, not a treatment trial. It may not lead to new therapies, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advancing Vision Research, LLC
Goodlettsville, Tennessee, 37072, United States
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Andover Eye Associates
Andover, Massachusetts, 01810, United States
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Butchertown Clinical Trials
Louisville, Kentucky, 40206, United States
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CORE Inc.
Shelby, North Carolina, 28150, United States
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Eye Research Foundation
Newport Beach, California, 92663, United States
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Oculus Research
Garner, North Carolina, 27529, United States
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Piedmont Eye Center
Lynchburg, Virginia, 24502-4271, United States
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Total Eyecare, P.A.
Memphis, Tennessee, 38119, United States