New eye drop cocktail aims to quench dry eye Sufferers' tears

NCT ID NCT07128628

Recruiting now Symptom relief Sponsor: Bausch & Lomb Incorporated Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests a new eye drop that combines two active ingredients—lifitegrast and perfluorohexyloctane—for people with dry eye disease. About 423 adults will use the drops twice daily for 4 weeks. Researchers will measure changes in eye surface staining and symptom scores to see if the combo works better than either ingredient alone or a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lifitegrast and perfluorohexyloctane eye drops

What this could lead to

If it works, this could offer a more effective twice-daily eye drop for dry eye symptoms like stinging and blurred vision.

What could go wrong

This is an early Phase 2 trial with only 4 weeks of treatment, so long-term benefits are unknown. The new combo may not work better than existing drops.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advancing Vision Research, LLC
RECRUITING

Smyrna, Tennessee, 37167, United States
Asheville Eye Associates
RECRUITING

Asheville, North Carolina, 28803, United States
Bowden Eye and Associates
RECRUITING

Jacksonville, Florida, 32256, United States
CORE Inc.
RECRUITING

Shelby, North Carolina, 28150, United States
Clayton Eye Clinical Research, LLC
RECRUITING

Morrow, Georgia, 30260, United States
Complete Eye Care of Medina
RECRUITING

Medina, Minnesota, 55340, United States
Comprehensive Eye Care Ltd.
RECRUITING

Washington, Missouri, 63090, United States
Eye Doctors of Arizona, PLLC
RECRUITING

Phoenix, Arizona, 85028, United States
Eye Research Foundation, Inc.
RECRUITING

Newport Beach, California, 92663, United States
Global Research Management, Inc.
RECRUITING

Glendale, California, 91204, United States
Insight Eyecare Specialties, Inc.
RECRUITING

Kansas City, Missouri, 64111, United States
Insight Research Clinic LLC.
RECRUITING

Powell, Ohio, 43065, United States
Intouch Clinical Research Center
RECRUITING

Houston, Texas, 77034, United States
Kannarr Eye Care, LLC
RECRUITING

Pittsburg, Kansas, 66762, United States
Lake Travis Eye and Laser Center
RECRUITING

Lakeway, Texas, 78738, United States
LoBue Laser and Eye Medical Center
RECRUITING

Murrieta, California, 92562, United States
Midwest Cornea Associates LLC
RECRUITING

Carmel, Indiana, 46032, United States
Moyes Eye Center, P.C.
RECRUITING

Kansas City, Missouri, 64154, United States
Oculus Research
RECRUITING

Garner, North Carolina, 27529, United States
Ophthalmology Consultants, Ltd.
RECRUITING

St Louis, Missouri, 63131, United States
Opthalmic consultants of Long Island
RECRUITING

Garden City, New York, 11530, United States
Rochester Ophthalmological Group,PC
RECRUITING

Rochester, New York, 14618, United States
Scott & Christie Eyecare Associates - The Surgery Center at Cranberry
RECRUITING

Cranberry Township, Pennsylvania, 16066, United States
Segal Drug Trials/Office of Bruce A Segal, MD
RECRUITING

Delray Beach, Florida, 33484, United States
Shettle Eye Research, Inc
RECRUITING

Largo, Florida, 33773, United States
SoCal Eye - Lakewood Clinic
RECRUITING

Long Beach, California, 90805, United States
Southern College of Optometry
RECRUITING

Memphis, Tennessee, 38104, United States
Total Eye Care PA
RECRUITING

Memphis, Tennessee, 38119, United States
Vance Thompson Vision - Alexandria
RECRUITING

Alexandria, Minnesota, 56308, United States
Vance Thompson Vision - Fargo, ND
RECRUITING

West Fargo, North Dakota, 58078, United States
West Bay Eye Associates
RECRUITING

Warwick, Rhode Island, 02888, United States
Wolstan and Goldberg Eye Associates
RECRUITING

Torrance, California, 90505, United States