New eye drops aim to soothe dry eye sufferers

NCT ID NCT06424444

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tested whether reproxalap eye drops can safely reduce discomfort in people with dry eye disease. 421 adults used the drops or a placebo for up to 6 weeks. The main goal was to measure changes in eye discomfort scores over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

reproxalap ophthalmic solution (0.25%)

What this could lead to

If successful, this could provide a new eye drop option to reduce discomfort in people with dry eye disease.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. The improvement over placebo may be small, and long-term safety is not fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Core, Inc.

    Shelby, North Carolina, 28150, United States