New eye drop shows promise for Sjogren's dry eye sufferers
NCT ID NCT05136170
First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 24 times
Summary
This study tested an eye drop called cenegermin (Oxervate) in 85 adults with severe dry eye caused by Sjogren's syndrome. Participants also used cyclosporine eye drops. The goal was to see if cenegermin could increase tear production and reduce dry eye symptoms better than a placebo over 4 to 16 weeks. Results focus on tear test scores and symptom questionnaires.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AOU Gaspare Rodolico - Ospedale San Marco
Catania, 95123, Italy
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AOU Policlinico Umberto I - Dipartimento Organi di Senso - Clinica Oculistica
Roma, 00161, Italy
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Houston Eye Associates HEA - Gramercy Location
Houston, Tennessee, 77025, United States
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Lugene Eye Institute - Glendale Office
Glendale, California, 91204, United States
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OCLI (Ophthalmic Consultants of Long Island)
Garden City, New York, 11530, United States
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Scheie Eye Institute
Philadelphia, Pennsylvania, 19104, United States
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The Johns Hopkins University
Baltimore, Maryland, 21218, United States
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Toyos Clinic - Nashville
Nashville, Tennessee, 37215, United States
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Tufts University School of Medicine (TUSM) - New England Eye Center/Tufts Medical Center
Boston, Massachusetts, 02111, United States
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Università degli Studi di Milano - Ospedale San Giuseppe - UO Oculistica
Milan, 20123, Italy
Conditions
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