Artificial blood could save trauma victims when banked blood is scarce

NCT ID NCT05756426

Recruiting now Knowledge-focused Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create a whole blood substitute by combining artificial oxygen carriers, plasma, and platelets. Researchers will test these mixtures in the lab using blood from 250 healthy volunteers to see if they can match the performance of real blood. The goal is to have a product that can be used in emergencies, like on battlefields or in remote areas, where banked blood is not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: artificial blood components (oxygen carrier, plasma analogue, platelet analogue)
What this could lead to: If successful, this could lead to a field-ready blood substitute that saves lives in trauma situations where real blood is not available.
What could go wrong: This is an early laboratory study with healthy volunteers donating blood for testing, not a treatment trial. The artificial blood may not work as well as real blood or could have unexpected side effects.

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Conditions

The condition(s) this trial relates to.

Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMODYNAMIC INSTABILITY HEMORRHAGE

Contacts and locations

Locations

University of Maryland Baltimore (UMB)
RECRUITING

Baltimore, Maryland, 21201, United States

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