HEMODYNAMIC INSTABILITY

This study tests whether combining transcutaneous electrical nerve stimulation (TENS) with isometric exercise can improve blood pressure in people with resistant hypertension. Resistant hypertension means blood pressure stays high despite taking three or more medications. The tri…

This study tests whether a 5-minute mindfulness-based breathing exercise, done just before spinal anesthesia, can reduce the common drop in blood pressure and ease anxiety in women having a planned C-section. Half of the 150 participants will do slow, guided breathing (about 6 br…

This study tests whether a more detailed way of tracking heart and blood pressure (called advanced hemodynamic monitoring) can reduce problems like low blood pressure or slow heart rate during a procedure called ERCP, which uses a scope to examine the bile ducts. About 32 adults …

This study looks at whether a simple neck ultrasound can help doctors predict if a patient needs more fluids during major abdominal surgery. About 84 adults having planned abdominal surgery will take part. The goal is to see if changes in blood flow in the carotid artery can reli…

This study looks at whether doctors can rely on feeling a patient's pulse (in the neck, groin, or wrist) to know if their blood pressure is dangerously low during shock. Researchers will compare pulse checks with standard blood pressure readings in 5,000 critically ill adults in …

This pilot study tests whether an AI-based system can help doctors better manage fluids and blood pressure during complex ovarian cancer surgery. The system uses special software to guide fluid infusions and predict drops in blood pressure. The goal is to reduce complications lik…

This study looks at how different types of anesthesia change blood flow and oxygen use in the brains of children. Up to 1,000 kids having an MRI scan will be asked to join. The goal is to learn more, not to test a new treatment.

This study compares a non-invasive continuous blood pressure monitor (ClearSight) to the standard arterial catheter in 50 adults undergoing coil embolization for unruptured brain aneurysms. The goal is to see if the non-invasive method can safely detect blood pressure changes and…

This study uses a special chamber that creates mild blood-pooling in the legs to safely mimic early blood loss in 120 healthy adults aged 20-45. Researchers will compare signals from different body monitors to see which one best detects the change. The goal is to find a more reli…

This study looks at whether using a special heart ultrasound (called TEE) during emergencies helps doctors make better decisions and improves patient outcomes. Researchers will track 1,000 critically ill adults in the ER or ICU who receive this test as part of their care. The goa…

This study is testing a new monitoring platform called HemoSphere Alta in 100 adults having heart or liver transplant surgery. The goal is to collect data to help improve the device, not to treat a disease. Participants must be at least 18 years old and already scheduled for a pu…

This study aims to create a whole blood substitute by combining artificial oxygen carriers, plasma, and platelets. Researchers will test these mixtures in the lab using blood from 250 healthy volunteers to see if they can match the performance of real blood. The goal is to have a…

This study looks at 30 infants (3-8 months old) having surgery for craniosynostosis, a condition where skull bones fuse too early. Researchers want to see if a new monitoring method (PRAM) can better track blood pressure and fluid loss than standard monitors. The goal is to impro…