Cure My Disease

Don't miss your cure!

 Log in / Sign up

Morning or afternoon surgery? study tests if body clock alters anesthesia safety

NCT ID NCT07686432

Knowledge-focused Sponsor: Jie Chen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study looks at whether having surgery in the morning versus the afternoon changes how well the sedative ciprofol works and how smoothly patients recover. Researchers will compare adults having non-emergency surgery starting between 8-11 AM or 2-5 PM. The goal is to see if the body's natural daily rhythm affects blood pressure drops during anesthesia and overall recovery quality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ciprofol
What this could lead to
If timing matters, doctors may schedule surgeries to improve anesthesia safety and recovery.
What could go wrong
This is an observational study, not a treatment test. Results may show no clear difference or may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 480 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for surgical procedures under general anesthesia.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged 18-65 years, with ASA physical status I-II. 2. Body Mass Index (BMI) between 18-30 kg/m². 3. Scheduled for elective non-cardiac and non-intracranial surgery under general anesthesia, with an expected operative duration of 1-2 hours. 4. Morning group: surgery start time between 08:00 and 11:00, with completion no later than 13:00; Afternoon group: surgery start time between 14:00 and 17:00, with completion no later than 19:00. 5. Willing to participate and having provided signed informed consent. Exclusion Criteria: 1. Severe hepatic or renal insufficiency (Child-Pugh Class C or eGFR \< 30 ml/min/1.73m²). 2. Severe cardiovascular, respiratory, or neurological diseases. 3. Long-term use of sedative-hypnotics, anxiolytics, antidepressants, or glucocorticoids. 4. Known allergy to ciprofol, propofol, or their excipients. 5. Recent (within 3 months) history of shift work, transmeridian travel, or other conditions that may cause circadian rhythm disruption. 6. Pregnant or lactating women. 7. Any other condition deemed by the investigator as unsuitable for participation in this study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anesthetics adverse reaction are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

channelopathy-associated congenital insensitivity to pain, autosomal recessive circadian rhythm sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthetics adverse reaction Ciprofol Circadian rhythm Hemodynamic instability

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.