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Blood test math may flag hidden risk of anesthesia danger

NCT ID NCT07804706

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

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Cancelled before anyone took part.

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When the status isn't known

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First seen Sep 04, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study looks at whether a simple calculation from routine blood tests, called the neutrophil percentage-to-albumin ratio (NPAR), can predict which patients will experience a dangerous drop in blood pressure after anesthesia begins. Researchers will follow 200 adults undergoing major cancer surgery under general anesthesia. They will record blood pressure and any use of medications to support it during the first 20 minutes after anesthesia induction, then check if the NPAR value from before surgery matches who had problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the ratio predicts blood pressure drops, doctors could identify high-risk patients before surgery and tailor anesthesia care to prevent complications.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The ratio may not reliably predict blood pressure issues in all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients aged 18 years or older who are scheduled to undergo elective major oncologic surgery under general anesthesia. Eligible participants must have available preoperative complete blood count and serum albumin measurements and undergo standard intraoperative hemodynamic monitoring. Patients will be enrolled consecutively at the study center. Individuals undergoing emergency surgery or presenting with preoperative hemodynamic instability, vasopressor or inotropic support, sepsis or active infection, hematologic malignancy, advanced cardiac, renal, or hepatic failure, pregnancy, or missing laboratory data will be excluded.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Scheduled for elective major oncologic surgery * Undergoing surgery under general anesthesia * Availability of preoperative complete blood count and serum albumin -measurements * Standard hemodynamic monitoring * Provision of written informed consent for participation in the study Exclusion Criteria: * Age younger than 18 years * Emergency surgery * Preoperative hemodynamic instability * Preoperative vasopressor or inotropic support * Sepsis or active infection * Hematologic malignancy * Advanced cardiac, renal, or hepatic failure * Pregnancy * Missing preoperative laboratory data -Inability to complete the 20-minute post-induction evaluation period-

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodynamic instability Post-induction hypotension (PIH)

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital

    RECRUITING

    Ankara, Yeni̇mahalle, Turkey (Türkiye)

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