A simple leg lift could forewarn dangerous blood pressure drops in surgery

NCT ID NCT07777159

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Recruiting now
This trial is taking on new participants right now.
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Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
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Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
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When the status isn't known

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First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This study tests whether a simple bedside maneuver—raising the legs—combined with ultrasound of the carotid artery can predict if a patient will experience a sudden drop in blood pressure after anesthesia is given. It involves adults undergoing elective surgery for gastrointestinal tumors. The goal is to find a reliable, non-invasive warning sign that could help doctors prevent complications during anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Passive leg raising maneuver and carotid artery Doppler ultrasound
What this could lead to
If successful, this could give anesthesiologists a simple, non-invasive way to predict and prevent dangerous blood pressure drops during surgery, improving patient safety.
What could go wrong
This is a small, early-stage study. The predictive accuracy may be limited, and results may not apply to all surgical patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 99 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 18 years or older who are scheduled for elective gastrointestinal tumor surgery under general anesthesia. Eligible participants will be ASA physical status I-III and have a BMI \<40 kg/m². Both sexes will be eligible.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Patients scheduled for elective gastrointestinal tumor surgery * Surgery planned under general anesthesia * Body mass index (BMI) \<40 kg/m² * Written informed consent provided Exclusion Criteria: * Refusal to participate or inability to obtain written informed consent * BMI ≥40 kg/m² * Pregnancy * Emergency surgery * Difficult intubation * ASA physical status ≥IV * Pediatric patients (\<18 years) * Inability to perform carotid Doppler measurements * Arrhythmia other than continuous sinus rhythm or uncontrolled cardiac arrhythmia * Severe cardiac dysfunction or left ventricular ejection fraction \<40% * Severe valvular heart disease * Clinically significant autonomic nervous system disorders * Inadequate noninvasive blood pressure monitoring or inability to obtain the required hemodynamic measurements * Active sepsis or systemic inflammatory syndrome * Severe peripheral vascular disease or significant carotid artery stenosis (\>50%) * Severe pulmonary disease or advanced respiratory failure * Implanted cardiac device (pacemaker/ICD) * Baseline mean arterial pressure (MAP) \<65 mmHg * Preoperative systolic blood pressure \>190 mmHg or diastolic blood pressure \>110 mmHg

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, 06100, Turkey (Türkiye)

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