A simple leg lift could forewarn dangerous blood pressure drops in surgery
NCT ID NCT07777159
First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time
Summary
This study tests whether a simple bedside maneuver—raising the legs—combined with ultrasound of the carotid artery can predict if a patient will experience a sudden drop in blood pressure after anesthesia is given. It involves adults undergoing elective surgery for gastrointestinal tumors. The goal is to find a reliable, non-invasive warning sign that could help doctors prevent complications during anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Passive leg raising maneuver and carotid artery Doppler ultrasound
- What this could lead to
- If successful, this could give anesthesiologists a simple, non-invasive way to predict and prevent dangerous blood pressure drops during surgery, improving patient safety.
- What could go wrong
- This is a small, early-stage study. The predictive accuracy may be limited, and results may not apply to all surgical patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 99 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults aged 18 years or older who are scheduled for elective gastrointestinal tumor surgery under general anesthesia. Eligible participants will be ASA physical status I-III and have a BMI \<40 kg/m². Both sexes will be eligible.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * Patients scheduled for elective gastrointestinal tumor surgery * Surgery planned under general anesthesia * Body mass index (BMI) \<40 kg/m² * Written informed consent provided Exclusion Criteria: * Refusal to participate or inability to obtain written informed consent * BMI ≥40 kg/m² * Pregnancy * Emergency surgery * Difficult intubation * ASA physical status ≥IV * Pediatric patients (\<18 years) * Inability to perform carotid Doppler measurements * Arrhythmia other than continuous sinus rhythm or uncontrolled cardiac arrhythmia * Severe cardiac dysfunction or left ventricular ejection fraction \<40% * Severe valvular heart disease * Clinically significant autonomic nervous system disorders * Inadequate noninvasive blood pressure monitoring or inability to obtain the required hemodynamic measurements * Active sepsis or systemic inflammatory syndrome * Severe peripheral vascular disease or significant carotid artery stenosis (\>50%) * Severe pulmonary disease or advanced respiratory failure * Implanted cardiac device (pacemaker/ICD) * Baseline mean arterial pressure (MAP) \<65 mmHg * Preoperative systolic blood pressure \>190 mmHg or diastolic blood pressure \>110 mmHg
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Bilkent City Hospital
Ankara, 06100, Turkey (Türkiye)
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