New stem cell transplant shows promise for kids with tough cancers
NCT ID NCT01625351
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new way to do stem cell transplants in 23 children with cancers that came back or didn't respond to treatment. The method removes certain immune cells from the donor's stem cells to help the child's body recover faster and fight infections better. The goal was to see if the transplant was safe and possible, and to track survival and recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- stem cell transplant with selective T-cell depletion
- What this could lead to
- If successful, this approach could make stem cell transplants safer and more effective for children with hard-to-treat cancers, potentially improving survival rates.
- What could go wrong
- This is an early phase I trial with only 23 participants, so results may not apply broadly. Risks include infection, graft failure, and side effects from chemotherapy and immune-suppressing drugs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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