Zinc pills tested as a simple way to lower blood sugar in prediabetes

NCT ID NCT05835037

Recruiting now Disease control Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study tests whether taking a daily 30 mg zinc supplement for one year can lower blood sugar and HbA1c levels in people with prediabetes. Two hundred Amish adults aged 18–80 with prediabetes will be randomly assigned to receive either zinc or a placebo pill. Researchers will compare changes in fasting glucose and HbA1c at 6 and 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: zinc gluconate (30 mg tablet daily)
What this could lead to: If it works, this could point toward a simple, low-cost supplement to help control blood sugar in people with prediabetes.
What could go wrong: This is a mid-stage trial with 200 participants, so results may not apply to everyone. Zinc supplements can cause stomach upset and may interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hyperglycemia prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERGLYCEMIA PREDIABETIC STATE

Contacts and locations

Locations

Amish Research Clinic
RECRUITING

Lancaster, Pennsylvania, 17602, United States

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