New hope for tough lung cancer: targeted pill takes on Chemo-Resistant tumors

NCT ID NCT05450965

First seen Jan 05, 2026 · Last updated Jun 03, 2026 · Updated 19 times

Summary

This study tests a drug called onvansertib in about 37 adults with small cell lung cancer that came back or didn't respond to chemo. Onvansertib blocks a protein (PLK1) that cancer cells need to repair themselves, aiming to shrink tumors. The main goal is to see how many patients have their tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Hillman Cancer Center

    ACTIVE_NOT_RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Maryland Greenebaum Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact

    Contact

Conditions

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