University Of Maryland, Baltimore

This study tested how well the drug primaquine prevents the return of P. vivax malaria in 160 people aged 15 and older. Participants had uncomplicated malaria and normal G6PD levels. The goal was to see if a full course of primaquine can cure the infection and stop future relapse…

This early-stage study tested a new oral vaccine designed to protect against two bacteria that cause severe diarrhea: Shigella and ETEC. Fifty-three healthy adults received the vaccine to check for side effects and to see if it triggers an immune response. The goal is to develop …

This pilot study tested whether using smart insulin pens together with continuous glucose monitors (CGMs) can improve blood sugar control in people with type 2 diabetes. Thirty adults with poorly controlled diabetes who use insulin took part. The goal was to see if this technolog…

This study tested a chewing gum with dietary nitrates (like those in leafy greens and beets) to see if it helps gum and heart health. Thirty adults with mild to moderate gum irritation or bleeding were randomly assigned to use either the nitrate gum or a placebo gum for three wee…

This study tested a new care model for 198 people who inject drugs and have hepatitis C. Participants received standard hepatitis C treatment along with HIV prevention medication (PrEP) and buprenorphine for opioid use disorder when needed. The goal was to cure hepatitis C, preve…

This early-phase study tested a combination of two drugs, pegcrisantaspase and venetoclax, in 27 adults whose acute myeloid leukemia had returned or not responded to prior treatments. The main goal was to check safety and find the best dose. Researchers also looked at how many pa…

This pilot study tested a counseling program designed for young adults (ages 13-35) who have early psychosis and use cannabis. The program aimed to reduce cannabis use and help manage psychosis symptoms. Seventeen participants completed the study, which focused on education and p…

This study tested whether H.P. Acthar Gel can improve symptoms and quality of life in people with CNS sarcoidosis, a rare condition where inflammation affects the brain and spinal cord. Four adults with the disease received the gel to see if it could control disease activity and …

This pilot study looked at whether giving e-cigarettes to adults aged 50 and older who are in treatment for opioid use disorder could help them cut down on smoking. The 36 participants were not trying to quit smoking at the start. Researchers measured how many people switched to …

This study looked at whether special hip muscle exercises could help older adults improve their balance and prevent falls. Researchers enrolled 97 generally healthy adults aged 65 and older. They compared high-velocity hip power training to conventional strength training to see w…

This study tested whether luteolin, a natural substance found in celery, green pepper, and chamomile tea, can improve symptoms of schizophrenia. 85 adults with schizophrenia or schizoaffective disorder took either luteolin or a placebo. The goal was to see if luteolin reduces ove…

This study tested whether virtual reality (VR) exercises can improve memory and thinking in older adults (65+) who had a mild traumatic brain injury. Thirty participants used VR cognitive games at home for 6 weeks. The goal was to see if VR could help with attention, memory, and …

This study looked at whether brief Christian prayer, given in person or virtually, can lower pain and anxiety in adults visiting a family medicine clinic. 180 participants with moderate or higher pain or anxiety were randomly assigned to receive prayer or listen to relaxing music…

This study tested whether adding duloxetine (a medication) to aerobic exercise helps older adults with both knee osteoarthritis and depression. 43 participants received the combined treatment. The goal was to see if it's feasible and if it improves pain and mood. Results may offe…

This study looked at whether gentle touch and massage therapy can help very premature babies in the NICU. Researchers wanted to see if these babies would gain weight faster, have less pain and stress, and be able to go home sooner. 32 babies were split into two groups: one receiv…

This study tested a new rehab program for people who had a stroke at least six months ago. It combined a robotic arm trainer with mild electrical pulses to the muscles. The goal was to see if this combo works better than the robot alone for improving arm movement and function. 24…

This study looked at whether suvorexant, an FDA-approved sleep medication, can improve daytime symptoms like fatigue, mood, and thinking in older adults with insomnia. Forty participants took either the drug or a placebo and used a smartphone app to report how they felt throughou…

This study tested a smartphone app called POSTHOC that helps cancer survivors manage symptoms and track healthy behaviors after finishing treatment. Fifty-one adults who recently completed cancer therapy used the app or received standard care for 12 weeks. The goal was to see if …

This study tested whether a home computer system could help veterans with multiple sclerosis do physical therapy exercises on their own. 51 participants used the system to track their exercises and check their balance and strength. The goal was to see if this approach is practica…

This study looked at how watching someone else experience pain relief can actually reduce your own pain. Researchers used brain scans to see which parts of the brain are involved in this effect. 211 healthy adults took part, and the goal was to understand the brain mechanisms beh…

This study tested whether a 6-week breathing muscle training program is feasible for typically developing children aged 6-12. Researchers measured how well children stuck with the training and how it affected their breathing during exercise. The goal was to understand the diaphra…

This study looked at whether a 6-week breathing muscle training program is doable for childhood cancer survivors and how it affects their breathing during exercise. Seven survivors who finished cancer treatment at least a year ago took part. The goal was to see if they could stic…

This study looked at whether two specially made estrogen creams deliver similar amounts of the hormone into the blood. Eight postmenopausal women aged 45 to 65 used both creams, and researchers measured hormone levels after single and repeated use. The goal was to check quality, …

This study tested a new way of reporting lab results for lung infections in patients on breathing machines. The goal was to see if it would help doctors avoid prescribing antibiotics when they aren't needed. The study involved 161 adults in intensive care units. Researchers compa…

This study looked at how epinephrine, a key hormone that helps raise blood sugar, affects blood vessel function and clotting in 32 healthy adults. Researchers measured changes in blood vessel widening before and after giving epinephrine. The goal was to better understand diabetes…

This study looked at how age and body fat affect inflammation in 100 veterans. Researchers wanted to see if losing a moderate amount of weight and increasing aerobic exercise could lower inflammation. Participants were overweight or obese but otherwise stable on their medical tre…

This study looked at how the supplement N-acetylcysteine (NAC) affects brain chemicals and thinking in 88 people with schizophrenia. Participants took tryptophan to raise a brain chemical called kynurenic acid, then received either NAC or a placebo. Researchers used memory tests …

This study tested a wellness program for long-term care workers to see if it could reduce stress and improve heart health. About 159 staff and residents took part. The program focused on healthy habits like diet, exercise, and stress management, and also looked at whether staff r…

This study looked at over 30,000 adults hospitalized in a statewide medical system to understand why some patients wait in the emergency department after being admitted (called boarding) and how this affects costs and care. Researchers analyzed existing medical records to find pa…

This study looked at how a non-invasive brain stimulation technique called TMS affects brain activity in people with schizophrenia. Ten participants received both real and fake TMS in separate sessions. Researchers measured brain connections and electrical signals before and afte…

This study looked at whether the antidepressant fluoxetine (Prozac) can improve the body's ability to respond to low blood sugar during exercise in people with type 1 diabetes. 64 adults (half with type 1 diabetes, half healthy) took either Prozac or a placebo for 8 weeks. The go…