Brain chemistry experiment seeks clues in schizophrenia

NCT ID NCT04013555

First seen Feb 11, 2026 · Last updated Apr 24, 2026 · Updated 12 times

Summary

This study looked at how a supplement called N-acetylcysteine (NAC) affects brain chemicals and thinking skills in people with schizophrenia. Researchers gave participants tryptophan (an amino acid) to raise a brain chemical called kynurenic acid, then used memory tests and MRI scans to see if NAC changed brain activity. The goal was to understand how these chemicals work, not to treat the disease directly.

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Contacts and locations

Locations

  • Maryland Psychiatric Research Center (MPRC) ; the Treatment Research Program (TRP)

    Catonsville, Maryland, 21228, United States

Conditions

Explore the condition pages connected to this study.