Can a common supplement tweak brain chemistry in schizophrenia?
NCT ID NCT04013555
First seen Feb 11, 2026 · Last updated Jun 06, 2026 · Updated 22 times
Summary
This study looked at how the supplement N-acetylcysteine (NAC) affects brain chemicals and thinking in 88 people with schizophrenia. Participants took tryptophan to raise a brain chemical called kynurenic acid, then received either NAC or a placebo. Researchers used memory tests and MRI scans to see if NAC could change brain activity and chemical levels.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Maryland Psychiatric Research Center (MPRC) ; the Treatment Research Program (TRP)
Catonsville, Maryland, 21228, United States
Conditions
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