New combo treatment aims to tackle deadly brain tumors
NCT ID NCT04699773
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a two-step treatment for people with newly diagnosed high-grade gliomas, a type of aggressive brain cancer. First, doctors use a laser to heat and destroy tumor tissue, then follow up with a shorter course of radiation. The goal is to see if this approach is safe and helps control the tumor. About 32 adults will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Laser interstitial thermal therapy (LITT) and hypofractionated radiation therapy
What this could lead to
If successful, this combination could offer a new, safer treatment option for people with aggressive brain tumors, potentially improving survival without severe side effects.
What could go wrong
This is an early-phase study with only 32 participants, so results may not apply to everyone. There is a risk of serious side effects like bleeding or neurological damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baltimore Washington Medical Center
RECRUITINGGlen Burnie, Maryland, 21061, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Central Maryland Radiation Oncology
RECRUITINGColumbia, Maryland, 21044, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-••••
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Maryland Proton Treatment Center
RECRUITINGBaltimore, Maryland, 21201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCH Kaufman Cancer Center
RECRUITINGBel Air, Maryland, 21014, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-••••
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University of Maryland Greenebaum Cancer Center
RECRUITINGBaltimore, Maryland, 21201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••