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Video game training may boost brain speed in schizophrenia

NCT ID NCT06641297

Recruiting now Knowledge-focused Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether learning to play a music video game like Guitar Hero can strengthen the brain's white matter in people with schizophrenia. White matter helps different brain regions communicate quickly, and it is often impaired in schizophrenia, leading to slower thinking. Researchers will use brain scans to measure changes in brain structure and chemistry before and after training. The goal is to understand if the brain can rewire itself with practice, potentially pointing to new ways to improve cognitive function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Music video game (Guitar Hero)
What this could lead to
If successful, this could point toward a new way to improve thinking speed and brain health in schizophrenia through simple, enjoyable training.
What could go wrong
This is a small, early-stage study focused on understanding brain changes, not a treatment. It may not lead to any direct benefit for participants or translate into a real-world therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

psychotic disorder schizoaffective disorder schizophrenia schizophreniform disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA DISORDERS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Maryland Psychiatric Research Center

    RECRUITING

    Catonsville, Maryland, 21228, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland Baltimore - Maryland Psychiatric Research Center

    NOT_YET_RECRUITING

    Catonsville, Maryland, 21228, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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