SCHIZOPHRENIA DISORDERS

This study is testing whether a weekly injection called tirzepatide, currently used for diabetes and weight loss, can help reduce heavy alcohol use in people who also have schizophrenia. About 108 participants will receive either the real drug or a placebo (dummy injection) for 2…

This study is testing a 12-week program called iTEST that combines daily cognitive exercises on a smartphone with personal coaching. The goal is to help adults with schizophrenia or similar conditions better judge their own abilities, which researchers believe could improve their…

This study is testing if a drug called diroximel fumarate, currently used for multiple sclerosis, can increase levels of a protective brain chemical called glutathione in people with schizophrenia. Researchers will use brain scans and other tests on 30 participants to see if the …

This is an early safety study for a new long-acting injection of the medication brexpiprazole, intended for schizophrenia. It will test single doses in 56 healthy volunteers and people with stable schizophrenia to check for side effects and see how the drug moves through the body…

This study aims to understand if practicing on a mock musical instrument can improve the brain's communication pathways in people with schizophrenia. Researchers will use brain scans to measure changes in white matter structure before and after the training. The goal is to learn …

This study aims to understand how brain activity in schizophrenia can be affected by non-invasive brain stimulation. Researchers will use a technique called theta burst stimulation on 60 participants with schizophrenia or epilepsy to measure brain wave changes. The goal is to gat…

This study aims to create a detailed health profile of 100 adults admitted to a general psychiatric hospital. Researchers will use questionnaires and medical records to measure the severity of mental illness, physical health problems, and treatment history. The goal is to see how…

This research study aims to collect health information and DNA samples from 50,000 people with serious mental illnesses like depression, bipolar disorder, schizophrenia, or dementia. Researchers will link this data with participants' medical records to look for patterns in geneti…

This study aims to find new brain-based markers for psychosis by measuring visual processing in people with schizophrenia, bipolar disorder, and healthy controls. Researchers will use EEG (electroencephalography) to record brain waves while participants view images. The goal is t…