Brain zaps for schizophrenia? new trial tests deep brain stimulation

NCT ID NCT07671261

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether deep brain stimulation (DBS) can help people with schizophrenia whose symptoms haven't improved with medication. First, doctors map the brain using electrodes to find the problem areas. Then, they implant a device that delivers mild electrical pulses to those spots. The trial involves 46 participants and will track symptom changes over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

deep brain stimulation (DBS) device

What this could lead to

If successful, this could offer a new treatment option for people with schizophrenia that hasn't improved with standard therapies.

What could go wrong

This is an early-stage trial with only 46 participants, so results may not apply to everyone. Brain surgery carries risks like infection or bleeding, and the treatment may not work for all.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ruijin Hospital, Shanghai JiaoTong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••