SCHIZO AFFECTIVE DISORDER

This study tests whether matching weight-loss medications to a person's specific obesity type (like 'hungry brain' or 'emotional hunger') helps people with bipolar disorder lose weight safely. About 100 adults aged 18-65 will take one of three FDA-approved drugs or join a weight-…

This study compares a new, lower-energy seizure therapy (LAP-ST) to standard electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression, bipolar disorder, or schizoaffective disorder. About 30 adults will receive one of the two treatments. Th…

This study tests whether cromoglicate, a drug used for allergies, can improve symptoms of schizophrenia when taken alongside standard medication. Researchers will enroll 160 adults aged 18-60 with schizophrenia or schizoaffective disorder. Participants will receive either cromogl…

This study tests an experimental medicine called BXCL501 to see if it can safely reduce sudden severe agitation in children aged 10-17 with schizophrenia or bipolar disorder. About 140 participants will receive either the drug or a placebo. The goal is to quickly calm symptoms li…

This study tests whether adding acetazolamide to standard antipsychotic medication can reduce symptoms in people with treatment-resistant schizophrenia. About 60 adults aged 18-55 will receive either acetazolamide or a placebo for a set period, while continuing their usual medica…

This study tests a virtual reality program designed to help people with psychosis improve their thinking and social skills. About 52 adults aged 18-60 with stable psychosis will use the program and do homework. The goal is to see if it's practical and helpful for daily life.

This study looks at how the brain processes visual information in people with schizophrenia, bipolar disorder, or schizoaffective disorder. Researchers will use EEG to measure brain activity while participants view images. The goal is to find early markers of psychosis that could…

This study looks at whether a gentle, non-invasive brain stimulation technique called tDCS can improve the ability to recognize emotions on people's faces in those with schizophrenia. Researchers will use brain scans (fMRI) and brain wave recordings (EEG) to see how the brain res…

This study uses a safe, noninvasive technique called transcranial magnetic stimulation (TMS) to understand how hallucinations happen in people with schizophrenia or schizoaffective disorder. Researchers will stimulate a specific brain circuit and measure changes in brain activity…