Could a common allergy spray help schizophrenia?
NCT ID NCT03794076
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether cromoglicate, a nasal spray used for allergies, can improve symptoms in people with schizophrenia or schizoaffective disorder. Researchers will give 160 adults either the active spray or a placebo, in addition to their usual medication. The goal is to see if it reduces positive symptoms like hallucinations or delusions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cromoglicate (NasalCrom) nasal spray
- What this could lead to
- If it works, this could offer a new add-on treatment to help control schizophrenia symptoms with fewer side effects.
- What could go wrong
- This is an early Phase 1/2 trial, so it is small and mainly tests safety. It may not show clear benefit, and the effect could be small or absent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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