Could a common drug help when schizophrenia treatments fail?

NCT ID NCT04887792

First seen Apr 14, 2026 · Last updated May 08, 2026 · Updated 3 times

Summary

This study tests whether adding acetazolamide to standard antipsychotic medication can reduce symptoms in people with treatment-resistant schizophrenia. About 60 adults aged 18-55 will receive either acetazolamide or a placebo for a set period, while continuing their usual medication. The main goal is to see if positive symptoms like hallucinations or delusions improve.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St John's Medical College Hospital

    RECRUITING

    Bangalore, India

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.