KNEE OSTEOARTHRITIS

This study is testing if a single injection of stem cells, collected from a person's own body fat, can safely reduce pain and improve function in a knee damaged by osteoarthritis. About 165 participants will be randomly assigned to receive either the stem cell injection or a plac…

This study aims to help patients and surgeons decide the best approach when both knees need replacement due to severe arthritis. It compares having both surgeries in one hospital stay versus having them months apart. Researchers will track recovery, pain, function, and overall qu…

This early-stage study is testing the safety of a new treatment for painful knee conditions. Doctors take a small amount of a patient's own bone marrow, grow special stem cells from it, and inject them back into the damaged knee. The goal is to see if this one-time injection is s…

This study compares two treatment approaches for knee osteoarthritis in military health system patients. All participants receive standard care based on military guidelines, while researchers examine whether adding early physical therapy referral improves outcomes. The study foll…

This study is testing a new way to manage hip and knee osteoarthritis pain. It compares whether having a physiotherapist as the first point of contact in a primary care team is better than the usual doctor-led care. The goal is to see if this approach improves patients' function …

This study is testing how well a specific partial knee replacement implant works for people with arthritis on the inner side of their knee. It follows 269 patients for up to 5 years after surgery to measure changes in pain, knee function, and daily activities. Researchers will al…

This study is testing if a procedure called cryoneurolysis can help manage pain after knee replacement surgery. Before surgery, half of the 100 participants will have specific nerves around their knee frozen, while the other half will receive a sham (fake) procedure. The main goa…

This study is testing whether an injection called biofiller PRP can help people with knee osteoarthritis. Researchers will give the injection to 60 participants to see if it reduces pain, improves knee movement and quality of life, and even increases the thickness of the protecti…

This study is testing whether a guided exercise program before knee replacement surgery helps patients recover better. Researchers are comparing patients who follow a standard exercise plan on their own to those who receive extra guidance and support from a 'patient navigator' be…

This study is testing if a new, smokeless laser heat therapy can help people with knee osteoarthritis feel better when added to their usual exercises. Researchers are comparing a standard exercise program to the same program plus the laser therapy over 8 weeks. They will measure …

This study is testing a robotic knee support device called Keeogo to see if it helps veterans with knee osteoarthritis move better and with less pain compared to their standard knee braces. Researchers will measure how well participants walk, climb stairs, and perform daily tasks…

This study is testing a new gel containing ketoprofen, a pain-relieving medication, that you rub on your skin over the knee. Researchers want to see if this gel can reduce pain and improve movement in people with knee osteoarthritis. The study involves 40 participants who will us…

This study is testing whether adding activity trackers, phone coaching, and financial rewards to standard recovery care can help people become more physically active after knee replacement surgery. Researchers enrolled 600 adults who had knee replacement for arthritis and randoml…

This study is testing whether a special decision-making tool helps patients with severe hip or knee osteoarthritis make better choices about joint replacement surgery. Researchers want to see if using this tool during doctor visits improves how informed patients feel, increases t…

This study is testing if a small implanted device that gently stimulates spinal nerves can reduce chronic pain from knee arthritis. It will involve 30 adults with long-term knee pain who haven't gotten enough relief from other treatments like physical therapy or injections. Parti…

This study is testing if a mind-body movement therapy can help people with knee osteoarthritis better than standard physical therapy or just doing exercises at home. The therapy, called Basic Body Awareness Therapy (BBAT), focuses on improving body awareness, posture, and movemen…

This study compares two different exercise programs to see which works better for reducing pain and improving function in women with knee osteoarthritis. 70 female participants will be randomly assigned to either closed kinetic chain exercises or isometric exercises for 4 weeks. …

This study is testing whether a home-based virtual reality (VR) exercise program can help people manage pain from knee osteoarthritis. Fifty participants will either use the VR games, which guide them through physiotherapy exercises, or follow a standard home exercise program for…

This study is comparing a new robotic-assisted surgical technique for partial knee replacement against traditional methods. It aims to see if using a robot helps place the implant more precisely and leads to less pain and better recovery for people with knee arthritis. The resear…

This study is testing whether a minimally invasive procedure called genicular artery embolization (GAE) works better than standard steroid injections for reducing pain from knee osteoarthritis. About 264 adults with ongoing knee pain who haven't gotten relief from basic treatment…

This study is testing whether combining two specific exercise approaches can help people with knee osteoarthritis feel less pain, move their knees more easily, and perform daily activities better. It will involve 40 participants aged 40-65 who have knee pain and stiffness. One gr…

This study aims to find the better method for reducing long-term pain after knee replacement surgery. It will compare two techniques that block pain signals from the knee nerves: one uses heat (radiofrequency) and the other uses a chemical (phenol). Researchers will follow 140 pa…

This study is testing if wrapping cabbage leaves around the knee can help reduce pain and improve movement for people with knee osteoarthritis. Researchers will compare two methods of applying the leaves against standard care in 90 participants over 4 weeks. The goal is to see if…

This study compares two different injection procedures for people with advanced knee osteoarthritis whose pain hasn't improved with standard treatments. Doctors are testing whether a chemical nerve block (phenol) provides longer-lasting pain relief and better function than a more…

This study is testing if a single injection into the knee can safely reduce pain and improve movement for people with moderate to severe knee osteoarthritis. The injection combines a patient's own platelet-rich plasma (PRP) with a gel-like fluid (HA) and is compared against a sta…

This study is testing if adding mental training exercises to standard physical therapy helps people recover better after knee replacement surgery. It will involve about 40 patients who have had surgery for knee arthritis. Participants will be split into groups to receive either s…

This study aimed to see if a short course of steroid pills (methylprednisolone), taken after knee replacement surgery, could help reduce pain, improve movement, and lessen the need for strong narcotic painkillers. It planned to enroll adults getting their first knee replacement. …

This study aims to see how stable a new type of porous knee implant is after surgery. It will follow 31 patients with knee osteoarthritis for two years, using special imaging to measure tiny movements of the implant and tracking patient pain, function, and satisfaction. The goal …

This study follows golfers who get hip, knee, or shoulder replacement surgery to see how many return to golf, how long it takes, and how their game changes. Researchers will track 124 patients for one year through questionnaires about their golf activity, mobility, and joint func…

This study aims to understand how vision affects a person's ability to sense their knee's position, a function often impaired by osteoarthritis. Researchers will measure knee position sense in 120 participants, both with and without visual feedback. The goal is to gather knowledg…

This study aims to understand how often people with knee osteoarthritis experience nerve-related pain and how it connects to the pain that wakes them up at night. Researchers will follow 150 patients to see if night pain is a sign of nerve pain and how both affect sleep quality a…