Mind over knee pain? study probes link between worry and osteoarthritis suffering

NCT ID NCT07609056

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This observational study looks at 103 adults with knee osteoarthritis to see if repetitive negative thinking (rumination and worry) is linked to worse pain and disability, even when X-ray damage is similar. Participants fill out questionnaires about their thoughts, pain, and daily function. The goal is to understand why some people hurt more than others with the same joint damage, which could lead to treatments that address both mind and body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fatih Sultan Mehmet Training and Research Hospital

    Istanbul, Atasehir, 34752, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could point toward adding psychological support to standard knee osteoarthritis care, potentially improving pain management without new drugs.

What could go wrong

This is an observational study, not a treatment trial. It only measures thoughts and pain at one time point, so it cannot prove that changing thinking reduces pain. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain rumination disorder Rumination Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.