OSTEO ARTHRITIS KNEE

This study is testing the safety and side effects of an experimental treatment called OA-SYS for people with moderate to severe knee osteoarthritis. OA-SYS is an injection containing adult stem cells, given directly into the painful knee joint. The main goal is to see if the trea…

This study is testing whether adding the common diabetes medication metformin to standard care can better control pain and potentially slow the progression of knee osteoarthritis. It will involve 70 adults aged 30-60 with moderate knee arthritis confirmed by X-ray. The main goal …

This study compares two types of knee replacement surgery for people with severe arthritis on the inner side of the knee. It tests whether a newer, robot-assisted partial knee replacement leads to better knee function and faster recovery than the traditional total knee replacemen…

This study is testing whether adding a special fall prevention program to standard physical therapy can reduce the number of falls in older adults recovering from total knee replacement. Researchers will compare two groups over 24 weeks: one receiving standard therapy and one rec…

This study is testing if a special breathing therapy, which involves breathing air with changing oxygen levels, can boost the benefits of standard physical therapy for knee osteoarthritis. It will involve 60 adults with knee pain to see if the combination improves pain, walking, …

This study is testing whether a new gel injection called Arthrosamid works better than the standard steroid injection for managing knee osteoarthritis pain. About 200 adults with moderate-to-severe knee arthritis will receive one injection of either the new gel or the standard tr…

This pilot study is testing whether a minimally invasive procedure called geniculate artery embolization, when added to standard care (physical therapy and medications), provides better and longer-lasting pain relief for knee osteoarthritis than standard care alone. Researchers w…

This study is testing a knee implant device called the MISHA Knee System to see if it safely reduces pain and improves function for people with osteoarthritis on the inner side of their knee. Researchers will follow 120 participants for five years after they receive the implant t…

This study is testing whether a new procedure using tiny, dissolvable beads injected into knee arteries works better than standard steroid injections for reducing arthritis pain. About 89 adults with moderate to severe knee osteoarthritis pain that hasn't improved with other trea…

This study is testing whether using a home vibration machine for 12 weeks can help reduce knee pain and inflammation in adults with osteoarthritis. Researchers want to see if this gentle, standing exercise is a tolerable alternative to more strenuous workouts. They will measure c…

This study is testing which type of knee injection works best for osteoarthritis pain and stiffness. Researchers are comparing platelet-rich plasma (PRP), hyaluronic acid gel, and a combination of both in 288 adults with knee arthritis. Participants receive one injection and are …

This study aims to find out which type and dose of vitamin K supplement works best for older adults with knee osteoarthritis. Researchers will measure vitamin levels in the blood of 55 participants to see how different supplements affect specific markers. The goal is to gather in…