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Walking retraining after ACL injury may stave off knee arthritis

NCT ID NCT05848622

Recruiting now Disease control Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a 6-week gait retraining program using real-time feedback can improve walking patterns and reduce early signs of knee osteoarthritis in people who have had ACL reconstruction. Seventy participants will be randomly assigned to receive either real-time biofeedback or a sham version. Researchers will measure changes in knee forces, cartilage health, and symptoms at 6 weeks and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

real-time gait biofeedback

What this could lead to

If it works, this could lead to a simple walking retraining program that helps prevent or delay knee osteoarthritis after ACL surgery.

What could go wrong

This is a small, early-stage study with only 70 participants. The training is short (6 weeks) and it's unclear if any benefits will last or if they truly prevent arthritis long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries articular cartilage disorder gait apraxia Knee Injuries osteoarthritis osteoarthritis, knee prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTERIOR CRUCIATE LIGAMENT INJURIES CARTILAGE, ARTICULAR GAIT KNEE INJURIES KNEE OSTEOARTHRITIS OSTEO ARTHRITIS KNEE POST-TRAUMATIC OSTEOARTHRITIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27516, United States