ANTERIOR CRUCIATE LIGAMENT INJURIES

This study compares two different tendon grafts used to repair a torn ACL in the knee: one from the hamstring and one from a leg muscle called peroneus longus. Sixty adults with an isolated ACL tear will be randomly assigned to receive one of the grafts during arthroscopic surger…

This study tests whether a platelet-rich plasma (PRP) injection given soon after an ACL tear can reduce inflammation and improve knee function, with the goal of lowering the risk of post-traumatic osteoarthritis later. About 56 people with a recent ACL injury will receive either …

This study tests whether a concentrated bone marrow injection (cBMA) can reduce pain and inflammation in people who develop knee arthritis after a second ACL reconstruction surgery. About 40 adults aged 18 to 55 will receive either cBMA with surgery or surgery alone. Researchers …

This study compares two common tendon grafts used in ACL reconstruction surgery: the semitendinosus (hamstring) graft and the quadriceps graft. Researchers want to see which one leads to better knee stability and function after surgery. About 200 people with ACL tears who plan to…

This study tests a new type of MRI scanner that may give clearer images of knee ligaments like the ACL. Current MRIs often miss these tissues, but the new method uses a special angle to make them visible. Researchers will scan 20 adults scheduled for ligament repair to see if thi…

This study is testing whether giving a drug called anakinra into the knee soon after an ACL tear can prevent arthritis from developing years later. About half of people with an ACL injury get arthritis within 10–20 years, even after surgery. The trial will enroll 32 active adults…

This study tests whether a program combining gradual exposure to feared movements and mindfulness meditation can help people who had ACL knee surgery feel less afraid of re-injury. Researchers will compare the program to a waitlist group in 50 participants aged 14-35 who are 6 mo…

This study tests whether visual-guided balance training helps people who had ACL reconstruction surgery recover knee function and walking ability better than standard rehab. About 45 patients and some healthy volunteers will participate. Researchers will measure joint movement, m…

This study looks at whether wearing a functional knee brace after ACL reconstruction helps people feel more confident and ready to return to sports. About 96 people aged 14 to 39 who have a complete ACL tear and want to get back to sports will take part. Half will wear a brace af…

This study looks at whether whole-body vibration therapy can reduce knee pain in people who have had ACL reconstruction surgery. About 50 adults aged 18 to 60 with ongoing knee pain after surgery will use a vibrating platform for 8 weeks. The goal is to see if this therapy improv…

This study tests a wearable knee sleeve called KneeStim that uses mild electrical pulses to help people walk better after ACL reconstruction. About 60 military cadets aged 17-27 will wear the sleeve during rehab and daily activities for 12 weeks. Researchers will compare a group …

This study looks at whether special balance exercises can help people who had ACL surgery. The goal is to see if these exercises improve balance, reduce fear of moving, and help the knee work better. About 50 adults between 20 and 40 years old who are two weeks past surgery will …

This study looks at whether adding blood flow restriction training (BFRT) to standard physical therapy helps teenagers recover leg strength and muscle size after ACL knee surgery. About 40 teens who had ACL reconstruction will be randomly assigned to either standard rehab or stan…

This study compares two surgical techniques for repairing a torn ACL, the main knee ligament. Forty adults with ACL injuries will be randomly assigned to one of two procedures. Researchers will measure knee stability, function, and re-tear rates over one year to see which method …

This study tests whether giving morphine directly into the bone during ACL surgery can lower pain and reduce the need for opioid painkillers afterward. About 84 adults aged 18-40 having ACL reconstruction will take part. Participants will report their pain and medication use dail…

This study aims to build a database of normal movement patterns in healthy athletes aged 10 to 65. Researchers will track participants for 12 months to see who gets injured, especially ACL tears. The goal is to better understand injury risk, not to test a treatment.

This study looks at whether having limited knee extension (more than 5 degrees) in the early weeks after ACL reconstruction affects how well the thigh muscles recover strength. Researchers will measure muscle strength and functional tests in 30 adults who had ACL repair with hams…

This study is testing whether a robot can help surgeons place bone tunnels more accurately during ACL reconstruction. About 30 people aged 10 to 45 who need ACL surgery will take part. The robot guides the drilling of the tunnels, and the researchers will compare the planned tunn…

This study looks at how the number of daily steps affects knee cartilage health in people who have had ACL reconstruction surgery. Researchers will use MRI scans to measure cartilage changes and track step counts over a week. The goal is to understand if low daily steps lead to w…

This study follows 500 people who are already scheduled for minimally invasive shoulder or knee surgery for sports injuries like torn ligaments or rotator cuff tears. Researchers will collect information about each person's injury, surgery, and recovery over two years to learn wh…