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Saving the ligament: a trial tests whether repairing a torn ACL beats replacing it

NCT ID NCT05584020

Recruiting now Disease control Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial compares two surgical approaches for acute anterior cruciate ligament (ACL) tears: repairing the native ligament with strong sutures versus the standard reconstruction that replaces it with a tendon graft. The study enrolls patients with certain tear types (Sherman grades I and II) who are treated within three weeks of injury. Researchers will measure knee function and symptoms over two years to see if repair can match or outperform reconstruction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
arthroscopic ACL repair surgery
What this could lead to
If successful, ACL repair could become a standard option for certain tears, preserving the natural ligament and avoiding complications from reconstruction.
What could go wrong
This is a relatively small, early-stage trial. Repair may not be as durable as reconstruction, and only specific tear types are eligible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTERIOR CRUCIATE LIGAMENT INJURIES

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-••••

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