Knee surgery showdown: which tendon graft works best?

NCT ID NCT05461326

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common tendon grafts used in ACL knee reconstruction: the quadriceps tendon and the patellar tendon. Researchers want to see which one gives better knee stability and function after surgery. The trial will enroll 100 people who need ACL surgery and follow their recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

quadriceps tendon autograft or patellar tendon autograft (surgical procedure)

What this could lead to

If one graft proves clearly better, it could become the preferred choice for ACL reconstruction, leading to more stable knees and better recovery for patients.

What could go wrong

This is a relatively small, early-stage trial (100 people) comparing two established procedures, so any differences may be small or not apply to everyone. Both grafts have known risks like pain or stiffness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries musculoskeletal system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UAB Hospital Highlands

    RECRUITING

    Birmingham, Alabama, 35205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact