ORTHOPEDIC DISORDER

This study compares two common tendon grafts used in ACL knee reconstruction: the quadriceps tendon and the patellar tendon. Researchers want to see which one gives better knee stability and function after surgery. The trial will enroll 100 people who need ACL surgery and follow …

This study tests whether giving tranexamic acid (TXA) during hip reconstruction in children reduces blood loss and the need for blood transfusions. About 400 children will be randomly assigned to receive TXA, a nerve block, or standard care. The goal is to make surgery safer and …

This study looks at whether doing breathing exercises before orthopedic surgery (like knee, hip, or fracture repair) can help your lungs work better after the operation. It involves 36 adults who have used tobacco and are at risk for breathing problems after surgery. Participants…

This study tests a web-based program called Web-TIRELESS that teaches mind-body skills to help people with painful non-traumatic upper-extremity conditions and risky substance use. The program includes four 30-minute sessions covering cognitive-behavioral strategies, activity pac…

This study looks at whether starting physical therapy 2 weeks after reverse total shoulder replacement (for a broken upper arm bone) is better than waiting 6 weeks. Ten adults aged 50-85 will be randomly assigned to one of the two rehab schedules. The goal is to see which timing …

This study watches 2000 people having hip or knee replacement surgery to see how long spinal anaesthesia lasts. The goal is to learn how the amount of anaesthetic affects timing, helping doctors decide if patients can safely go home the same day. No new treatments are tested—just…

This study follows 4,000 children who receive orthopedic implants (like rods or screws) during standard care for bone fractures, deformities, or hip problems. Researchers will track how long the implants last, any complications, and how well they work over time. The goal is to ga…

This study is a registry that collects information on how well the CERAMENT bone void filler works in everyday medical practice. About 300 people receiving the filler during surgery will be followed for up to 18 months. The goal is to track any unexpected device issues, side effe…

This study follows 100 people who had total ankle replacement for arthritis. Researchers want to see if the implants last 10 years and how well patients do when the surgery is performed by surgeons who did not design the implant. Participants will have regular check-ups, X-rays, …

This study looks at how the size and type of rotator cuff tear affects the suprascapular nerve in the shoulder. Researchers will use MRI scans and nerve tests on 250 adults to see which tears cause nerve damage. They also want to find out if surgical repair can help the nerve rec…