ORTHOPEDIC DISORDER

This study tests whether giving children a medicine called tranexamic acid (TXA) during hip reconstruction surgery can reduce blood loss and the need for blood transfusions. About 400 children scheduled for hip surgery will be randomly assigned to receive TXA or a placebo. The go…

This study tests whether a web-based mind-body program can help adults with painful upper-arm conditions who also use substances like alcohol or cannabis in risky ways. About 50 participants will be randomly assigned to the program or a basic online education group. The goal is t…

This study follows 4,000 children who receive orthopedic implants (like rods, screws, or plates) for broken bones, limb deformities, or hip problems. Researchers will track how well the implants work, how long they last, and any side effects. The goal is to make sure these device…

This study looks at how the size and type of a rotator cuff tear (a common shoulder injury) can damage the suprascapular nerve, which controls shoulder muscles. Researchers will study 250 adults with confirmed tears using MRI scans and nerve tests. The goal is to understand when …

This study is a registry that collects information on how well the CERAMENT bone void filler works when used in normal medical practice. About 300 people who receive the filler as part of their treatment will be followed for up to 18 months. The goal is to track any unexpected de…

This study watches 2,000 people having hip or knee replacement surgery to see how long spinal anaesthesia lasts. The goal is to learn how the amount of anaesthetic affects timing, so doctors can better plan same-day discharge. No new treatments are tested—only observations are ma…

This study follows 100 people who had total ankle replacement surgery for arthritis. Researchers want to see how long the artificial joints last and how well patients do when the surgery is performed by surgeons who did not help design the implant. Participants will be tracked fo…