Knee surgery showdown: which graft works best for torn ACL?

NCT ID NCT04295148

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two common surgical grafts used to repair a torn anterior cruciate ligament (ACL): the semitendinosus hamstring tendon and the quadriceps tendon-bone graft. Researchers will enroll 200 active adults who recently tore their ACL and plan to return to sports. The main goal is to see which graft provides better knee stability and patient-reported function over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ACL reconstruction surgery using either a semitendinosus tendon graft or a quadriceps tendon-bone graft
What this could lead to
If successful, this study could show which graft type leads to better knee stability and function after ACL surgery, helping surgeons choose the best option for active patients.
What could go wrong
This is a relatively small, early-stage trial (200 participants) comparing two established surgical techniques, so differences may be small or not apply to all patients. As with any surgery, risks include infection, graft failure, and complications from anesthesia.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Capio Artro Clinic AB

    RECRUITING

    Stockholm, Stockholm County, 11428, Sweden

    Contact

    Contact

    Contact

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