Knee injection after ACL tear may stop arthritis before it starts

NCT ID NCT03968913

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a drug called anakinra into the knee within two weeks of an ACL injury can prevent arthritis that often develops years later. Half of the 32 participants will receive the drug, and half will receive a placebo (salt water). Researchers will track pain, function, and cartilage health using MRI and urine tests for two years after surgery.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries osteoarthritis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••