Early knee injection may stop arthritis after ACL injury

NCT ID NCT03968913

First seen Jan 26, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study is testing whether giving a drug called anakinra into the knee soon after an ACL tear can prevent arthritis from developing years later. About half of people with an ACL injury get arthritis within 10–20 years, even after surgery. The trial will enroll 32 active adults aged 18–35 who will receive either the drug or a placebo injection, and researchers will track their knee health using MRI scans, urine tests, and symptom surveys for two years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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