Fat cells to the rescue? new treatment for arthritic knees enters human testing

NCT ID NCT06485843

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new treatment called OA-SYS, made from cells taken from fat tissue, for people with moderate to severe knee osteoarthritis. The main goal is to see if it is safe and tolerable. 400 adults aged 35-75 with knee arthritis will receive the treatment and be monitored for side effects and changes in pain and function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OA-SYS (cells from fat tissue)

What this could lead to

If safe and effective, OA-SYS could offer a new way to manage knee osteoarthritis pain and reduce reliance on painkillers.

What could go wrong

This is an early Phase IIb trial focused on safety, not yet proven to work. The treatment involves cells from fat, and long-term benefits or risks are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Orthopedic & Sports Medicine Institute of Las Vegas

    RECRUITING

    Las Vegas, Nevada, 89117, United States

    Contact