OSTEO ARTHRITIS KNEE

This study tested a new medicine called LEVI-04 to see if it can reduce pain in people with knee osteoarthritis. About 518 adults with knee pain took either the drug or a placebo. The main goal was to measure pain changes using standard pain scales. The trial is complete, and res…

This study looked at whether a gentle movement technique called Mulligan mobilization can reduce pain and improve muscle function in people with knee osteoarthritis. Researchers measured pain, muscle activity, and sensory changes in 36 adults aged 50-70 with moderate knee arthrit…

This study compared sterile amniotic fluid injections to standard corticosteroid shots for knee osteoarthritis. 60 adults with moderate knee arthritis received either treatment, and researchers tracked how many needed extra pain relief within 6 months. The goal was to see if amni…

This study tested a hands-on therapy called Mulligan's mobilization, combined with isometric (holding) exercises, for people with knee osteoarthritis. Fifty adults aged 40-65 with moderate knee arthritis took part. The goal was to see if this approach could reduce pain, improve m…

This early-stage study tested whether injecting a special mixture of a person's own fat cells into their knee is safe for treating osteoarthritis. Nine adults aged 40-75 with knee arthritis took part. The main goal was to check for side effects, not to measure how well it works.

This study looked at whether adding a topical pain-relief cream to a supervised exercise program helps knee osteoarthritis more than either treatment alone. 79 adults aged 40-65 with moderate knee OA participated. The goal was to measure changes in pain and daily function over ti…

This study tested a once-weekly medicine called retatrutide in 445 adults who are overweight or have obesity and also have knee osteoarthritis. The goal was to see if it can reduce knee pain and help with weight loss compared to a placebo. The trial lasted about 77 weeks and meas…

This study looked at whether adding deep breathing or simple yoga poses to standard physical therapy could help people with knee osteoarthritis feel less afraid of moving. 40 adults aged 40-60 with severe knee pain took part. The results showed both approaches helped reduce fear …

This study tested a device called the OrthoCor Advanced System in 23 adults with knee osteoarthritis. The device uses heat and pulsed electromagnetic field (PEMF) therapy to try to reduce pain and improve movement. Participants used the device for 30 minutes twice a day for 4 wee…

This study tested whether using a cold and compression brace for six weeks after knee replacement surgery helps reduce pain and the need for strong painkillers. 208 adults who had a total or partial knee replacement took part. Participants used the brace five times a day for 20 m…

This study tested a 2-week at-home treatment for knee osteoarthritis pain in 208 older adults. Participants used a mild brain stimulation device (tDCS) while practicing mindfulness meditation. The goal was to see if this combination could reduce pain and improve daily function. R…

This study tested a web-based system that creates a personalized care plan for people with knee or hip osteoarthritis. The goal was to help patients and their doctors make more informed decisions about treatments, including whether to have joint replacement surgery. Over 5,700 ad…

This study looked at 60 adults aged 40-65 with knee osteoarthritis to see if testing muscle strength and performance differs when doing one task at a time versus two tasks at once. Participants completed strength tests, a sit-stand test, and pain questionnaires. The goal was to b…