OSTEO ARTHRITIS KNEE

This study tested a weekly injection called LY3437943 (retatrutide) in people who are overweight or have obesity and also have painful knee osteoarthritis. The main goals were to see if the treatment safely reduced knee pain and helped participants lose weight over about 77 weeks…

This small, early-stage study from the Mayo Clinic tested whether it is safe and practical to treat knee osteoarthritis by injecting a person's own processed fat cells into the joint. Nine participants with moderate arthritis received the injection to see if it caused any serious…

This study tested whether an investigational drug called LEVI-04 could safely reduce pain and improve physical function in people with knee osteoarthritis. Over 500 participants with moderate to severe knee pain received either the drug or a placebo injection. The main goal was t…

This study tested whether an injection of sterile amniotic fluid works better than the standard steroid injection to reduce pain and improve movement in people with knee osteoarthritis. 60 adults with ongoing knee pain received one type of injection without knowing which one. Res…

This study tested a portable device called the OrthoCor Advanced System to see if it could improve pain and quality of life for people with knee osteoarthritis. Participants used the device, which delivers gentle electromagnetic pulses and heat, for 30 minutes twice a day for 4 w…

This study tested whether deep breathing exercises or specific yoga poses were better at reducing the fear of movement in people with painful knee arthritis. Forty participants received either deep breathing or yoga, along with standard physiotherapy. Researchers measured changes…

This study tested which approach works better for easing knee arthritis pain and stiffness: a supervised exercise program, a topical anti-inflammatory cream, or using both together. It involved 79 adults with moderate knee arthritis. Researchers measured changes in pain, walking …

This study tested whether a specific hands-on physical therapy technique, when added to standard strengthening exercises, could better reduce pain and improve movement in people with knee osteoarthritis. It involved 50 adults aged 40-65 with moderate knee arthritis. Participants …

This study tested whether using a cold and compression brace for the first six weeks after a total or partial knee replacement helps patients recover better. Researchers wanted to see if this therapy could reduce pain at rest, lower the need for strong painkillers (opioids), and …

This study tested a hands-on physical therapy technique called movement mobilization to see if it could help people with knee osteoarthritis. Researchers worked with 36 patients to measure changes in their pain levels, muscle activity, and joint sensitivity. The goal was to see i…

This study tested whether a two-week home program combining gentle brain stimulation (tDCS) with mindfulness meditation could help older adults better manage knee osteoarthritis pain. It involved 208 participants with significant knee pain. The goal was to see if this combination…

This study tested a web-based, personalized care plan to help people with knee or hip osteoarthritis make better-informed decisions about their treatment. Over 5,700 patients worked with their doctors to use this tool, which provided information on pain trends, treatment options,…

This study aimed to understand how performing two tasks at once (like walking while talking) affects muscle strength and balance tests in people with knee osteoarthritis. Researchers compared standard single-task tests with dual-task tests in 60 adults aged 40-65 with knee arthri…