Can nerve stimulation plus exercise ease knee pain in seniors?
NCT ID NCT07258693
First seen Jan 03, 2026
Summary
This study tests whether adding a type of nerve stimulation (NESA or TENS) to a supervised exercise program can better reduce pain, improve function, and boost mental health in people over 60 with knee osteoarthritis. Over 8 weeks, 110 participants will receive either exercise plus NESA or exercise plus TENS. Researchers will measure pain, mobility, strength, sleep, and mood to see which combination works best.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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ICOT rehabilitation centers
Las Palmas de Gran Canaria, Spain
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
therapeutic exercise combined with noninvasive neuromodulation (NESA) or transcutaneous electrical nerve stimulation (TENS)
What this could lead to
If this works, it could point toward a more effective, drug-free way to reduce pain and improve mobility and mental health for older adults with knee osteoarthritis.
What could go wrong
This is a small, early-stage study with no blinding, so results may be influenced by participant expectations. The treatments are noninvasive and low-risk, but the added benefit of NESA over TENS is uncertain.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.