Can nerve stimulation plus exercise ease knee pain in seniors?
NCT ID NCT07258693
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This study tests whether adding a type of nerve stimulation (NESA or TENS) to a supervised exercise program can better reduce pain, improve function, and boost mental health in people over 60 with knee osteoarthritis. Over 8 weeks, 110 participants will receive either exercise plus NESA or exercise plus TENS. Researchers will measure pain, mobility, strength, sleep, and mood to see which combination works best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- therapeutic exercise combined with noninvasive neuromodulation (NESA) or transcutaneous electrical nerve stimulation (TENS)
- What this could lead to
- If this works, it could point toward a more effective, drug-free way to reduce pain and improve mobility and mental health for older adults with knee osteoarthritis.
- What could go wrong
- This is a small, early-stage study with no blinding, so results may be influenced by participant expectations. The treatments are noninvasive and low-risk, but the added benefit of NESA over TENS is uncertain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
ICOT rehabilitation centers
Las Palmas de Gran Canaria, Spain
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