Simple knee moves may cut arthritis pain without drugs

NCT ID NCT05577403

Completed Symptom relief Sponsor: Majmaah University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether adding a gentle joint-gliding technique called Mulligan's mobilization to simple isometric exercises could help people with knee osteoarthritis. Fifty adults with moderate knee arthritis received either the mobilization plus exercises or a sham version for three weeks. Researchers measured pain, range of motion, and disability before and after treatment to see if the combination worked better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mulligan's mobilization with movement plus isometric exercises
What this could lead to: If it works, this could offer a simple, drug-free way to reduce pain and improve movement for people with knee osteoarthritis.
What could go wrong: This is a small, completed trial with only 50 participants, so results may not apply to everyone. The treatment is a physical therapy technique, not a cure, and benefits may be modest.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEO ARTHRITIS KNEE

Contacts and locations

Locations

Rehabilitation center, Majmaah University

Al Majma'ah, Riyadh Region, 15341, Saudi Arabia

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