Can a cold brace ease pain after knee replacement?

NCT ID NCT05572359

Completed Symptom relief Sponsor: Martini Hospital Groningen Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether using a cold and compression brace for six weeks after knee replacement surgery helps reduce pain and the need for painkillers. 208 patients who had a total or partial knee replacement were asked to use the brace five times a day for up to 20 minutes. Researchers compared their recovery to patients who received usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cryo-and compression brace
What this could lead to: If it works, this could provide a simple, drug-free way to manage pain and improve recovery after knee replacement surgery.
What could go wrong: This is a completed trial, but the results are not yet widely known. The brace may not significantly reduce pain or opioid use compared to usual care, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEO ARTHRITIS KNEE

Contacts and locations

Locations

Martini ziekenhuis

Groningen, Provincie Groningen, 9728NT, Netherlands

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