KNEE OSTEOARTHRITIS
Clinical trials for KNEE OSTEOARTHRITIS explained in plain language.
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Fat cells injected into arthritic joints to ease pain
Disease control TerminatedThis study tested a one-time treatment for osteoarthritis using a patient's own regenerative cells taken from their body fat. Doctors injected these processed cells into painful joints like the knee, hip, or shoulder. The goal was to see if the treatment was safe and if it could …
Matched conditions: KNEE OSTEOARTHRITIS
Sponsor: Sanford Health • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Could a single shot slow knee arthritis? early trial halted
Disease control TerminatedThis study tested an experimental injection called lorecivivint for people with painful knee osteoarthritis. The main goal was to see if the injection could improve the health of knee cartilage, measured by MRI scans over one year. The trial was small and ended early due to COVID…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: PHASE2 • Sponsor: Biosplice Therapeutics, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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Halted trial tests potential knee arthritis breakthrough
Disease control TerminatedThis study tested two experimental drugs, canakinumab and LNA043, given as injections directly into the knee joint of people with painful knee osteoarthritis. The goal was to see if these drugs could reduce pain, improve function, and potentially protect or even regrow knee carti…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Custom knee implants tested for Long-Term safety
Symptom relief TerminatedThis study evaluated a custom-designed knee replacement system for people with severe osteoarthritis. Researchers followed 52 patients in Germany for up to 10 years after surgery to track complications related to the device or procedure. The goal was to understand the long-term s…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: NA • Sponsor: Restor3D • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Five-Year knee implant study seeks to improve joint replacement outcomes
Symptom relief TerminatedThis study followed 723 people with severe knee arthritis who received P.F.C. Sigma knee replacement implants. Researchers tracked how well the implants worked and how patients felt before surgery and for at least five years afterward. The goal was to collect real-world data on p…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: PHASE4 • Sponsor: DePuy International • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Can a new way of running heal Soldiers' knees?
Symptom relief TerminatedThis study aimed to see if teaching a specific running technique helps soldiers recover better from ACL knee surgery. It compared a special gait retraining program to a standard return-to-running plan. The goal was to reduce knee pain, improve function, and possibly lower the ris…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: NA • Sponsor: Keller Army Community Hospital • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Home workouts vs. physical therapy: can an app ease knee pain?
Symptom relief TerminatedThis study tested if a digital home exercise program could work as well as standard physical therapy for people with chronic knee osteoarthritis pain. Participants were randomly assigned to either use the SimpleTherapy app at home or receive traditional physical therapy for six w…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Symptom relief
Last updated Mar 16, 2026 15:26 UTC