KNEE OSTEOARTHRITIS
Clinical trials for KNEE OSTEOARTHRITIS explained in plain language.
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Fat cell therapy for arthritis falls short in early trial
Disease control TerminatedThis study tested whether a person's own fat-derived cells could safely reduce pain and improve movement in osteoarthritis of the knee, hip, ankle, shoulder, or wrist. Only 14 people enrolled before the study was stopped early. The main goal was to check safety and track pain and…
Matched conditions: KNEE OSTEOARTHRITIS
Sponsor: Sanford Health • Aim: Disease control
Last updated May 17, 2026 21:24 UTC
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Knee implant study tracks 723 patients over 5 years
Disease control TerminatedThis study followed 723 people with knee osteoarthritis who received a P.F.C. Sigma total knee replacement. The goal was to see how well the implant worked over at least 5 years by checking X-rays, physical exams, and patient questionnaires. Researchers also recorded any complica…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: PHASE4 • Sponsor: DePuy International • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Knee OA injection study halted early
Disease control TerminatedThis study tested an injection called lorecivivint for people with moderate to severe knee osteoarthritis. The goal was to see if it could improve cartilage health in the knee, measured by MRI scans. Only 13 people took part before the study was stopped early. The treatment aims …
Matched conditions: KNEE OSTEOARTHRITIS
Phase: PHASE2 • Sponsor: Biosplice Therapeutics, Inc. • Aim: Disease control
Last updated May 11, 2026 20:37 UTC
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Custom knee implant study ends early – what happened?
Disease control TerminatedThis study looked at how well a custom knee replacement system worked for people with knee osteoarthritis. Researchers tracked complications in 52 adults who had the surgery. The study was stopped early, so results are limited.
Matched conditions: KNEE OSTEOARTHRITIS
Phase: NA • Sponsor: Restor3D • Aim: Disease control
Last updated May 05, 2026 11:53 UTC
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Knee OA drug combo study halted early – what we know
Symptom relief TerminatedThis study tested two drugs, canakinumab and LNA043, injected into the knee to see if they could ease pain and protect cartilage in people with knee osteoarthritis. It included 23 adults with moderate to severe knee pain. The study was terminated early, so results are limited.
Matched conditions: KNEE OSTEOARTHRITIS
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 17, 2026 21:12 UTC
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At-Home digital workout rivals physical therapy for knee pain
Symptom relief TerminatedThis study compared a six-week digital home exercise program (SimpleTherapy) to standard physical therapy for people with chronic knee osteoarthritis pain. Researchers wanted to see if the at-home program was just as effective at improving knee symptoms and function. The study en…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC
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New running technique may ease pain after ACL surgery
Symptom relief TerminatedThis study looked at whether teaching people recovering from ACL surgery to run with a forefoot strike and slightly faster steps could reduce knee pain and improve function. Ten active-duty soldiers and cadets participated, comparing the new running technique to a standard walk-t…
Matched conditions: KNEE OSTEOARTHRITIS
Phase: NA • Sponsor: Keller Army Community Hospital • Aim: Symptom relief
Last updated May 06, 2026 16:15 UTC