Knee OA drug combo trial ends early — only 23 enrolled

NCT ID NCT04814368

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two injected drugs, canakinumab and LNA043, for people with painful knee osteoarthritis. It aimed to see if they could reduce pain and improve cartilage. The trial was stopped early and included only 23 participants, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Arthralgia osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Res Of W Florida

    Clearwater, Florida, 33765, United States

  • Horizon Clinical Research

    La Mesa, California, 91942, United States

  • LV Research

    Las Vegas, Nevada, 89119, United States

  • Lucas Research

    Morehead City, North Carolina, 28557, United States

  • Novartis Investigative Site

    Prague, Czech Republic, 19000, Czechia

  • Novartis Investigative Site

    Tartu, 50406, Estonia

  • Novartis Investigative Site

    Kecskemét, Bács-Kiskun county, 6044, Hungary

  • Novartis Investigative Site

    Budapest, 1036, Hungary

  • Novartis Investigative Site

    Riga, 1005, Latvia

  • Novartis Investigative Site

    Warsaw, 02-677, Poland

  • Precision Clinical Research LLC

    Sunrise, Florida, 33351, United States